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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
منشور في 2016"…L1-CAM KD led to the simultaneous downregulation of MycN, but the upregulation of PTEN protein expression. Notably, radiotherapy (2 Gy) of the IMR-32 cells led to significant upregulation of both L1-CAM and MycN, which was abrogated with L1-CAM KD in our cells. …"
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A comparison of peer, teacher and self-feedback on the reduction of language errors in student essays
منشور في 2016"…However, comparison of students' performance on lexical errors at the immediate post-test revealed that the self-feedback group significantly decreased this error percentage compared to the peer feedback group. …"
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Polarimetric SAR Speckle Reduction by Hybrid Iterative Filtering
منشور في 2020"…Speckle filtering in synthetic aperture radar polarimetry (PolSAR) is essential for the extraction of significant information. In this study, the authors introduced a hybrid iterative filtering scheme. …"
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
منشور في 2024"…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …"
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Gene expression data analysis identifies multiple deregulated pathways in patients with asthma
منشور في 2018"…The data highlight the multifactorial nature of asthma, but revealed no significant overlap with the gene expression profiles from different datasets interrogated in current studies. …"
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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
منشور في 2023"…RNA sequencing analysis demonstrated significant reduction in the mRNA expression of genes involved in the development and function of exocrine and endocrine pancreas. …"
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Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells
منشور في 2023"…Furthermore, we constructed co-expression networks linking significantly downregulated lncRNAs with differentially expressed pancreatic mRNAs.…"
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Genome-wide differential expression profiling of long non-coding RNAs (lncRNAs) in pancreatic cells derived from FOXA2-/- iPSCs
منشور في 2023"…Downregulation of FOXA2 expression during differentiation of induced pluripotent stem cells (iPSCs) into pancreatic islets leads to a significant reduction in α-and β-cell masses. …"
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DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression
منشور في 2015"…Nevertheless, DNAJB3 expression pattern in diabetic subjects and its mode of action are not yet known. …"
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
منشور في 2021"…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …"
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Effect of consanguinity on birth weight for gestational age in a developing country
منشور في 2007"…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …"
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Chemical composition, antioxidant and anti-inflammatory activity evaluation of the lebanese propolis extract
منشور في 2019"…Results: Pathology analysis revealed in the treated group significant reduction of immune cell infiltration and edema. …"
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"
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RFX3 is essential for the generation of functional human pancreatic islets from stem cells
منشور في 2025"…The loss of <i>RFX3</i> disrupted pancreatic endocrine gene regulation, reduced the number of hormone-secreting islet cells and impaired beta cell function and insulin secretion. Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …"
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The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells
منشور في 2023"…At the protein expression level, our results demonstrated that MSCs-CM (50%) enhanced the expression of the detoxifying NQO1in MGO-injured cells.…"
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Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
منشور في 2025"…AB-FUBINACA treatment also causes a significant dose related decrease in sperm viability. …"