The Effect of Different Doses of Intravenous Dexmedetomidine on the Properties of Subarachnoid Blockade: A Systematic Review and Meta-Analysis حسب Mohammad K Al Nobani (16561248)

"…We analyzed the duration of sensory and motor blockade and the related adverse effects in relation to different doses of IV dexmedetomidine.</p><p><b>Results:</b> Intravenous dexmedetomidine, with loading dose of 1 mcg/kg, prolonged the sensory blockade duration of spinal anaesthesia by a mean difference of 49.6 min, P<0.001, and motor blockade duration by a mean difference of 44.7 min, P<0.001, while a loading dose of 0.5 mcg/kg prolonged the sensory blockade by a mean difference of 43.06 min, P<0.001, and motor blockade duration by a mean difference of 29.09 min, P<0.001. …"

Effect of age and sex on warfarin dosing حسب Khoury, Ghada

"…The primary outcome assessed was warfarin total weekly dose (TWD). Results There was a statistically significant difference in the TWD among the ages (P<0.01); older patients required lower doses. …"
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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... حسب Saeid Safiri (3713035)

"…Bladder cancer accounted for 4.39 million (4.09 to 4.70) DALYs in 2019, and the age-standardised DALY rate decreased significantly by 18.6% (11.2 to 24.3) during the period 1990–2019. …"

Factors Influencing the Magnitude and Clinical Significance of Drug Interactions Between Azole Antifungals and Select Immunosuppressants حسب Saad, Aline

"…By bringing similarities and differences among these agents and their potential interactions to clinicians’ attention, they can appreciate and apply these findings in a individualized patient approach rather than follow only the one-size-fits-all dosing recommendations suggested in many tertiary references. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"

Investigating the Effect of Patient-Related Factors on Computed Tomography Radiation Dose Using Regression and Correlation Analysis حسب AlShurbaji, Mohammad

"…Investigating the relationships between the different dose indices, statistically significant relationships were found between all dose indices. …"
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Enoxaparin dosing for venous thromboembolism prophylaxis in hospitalized underweight adult patients: a retrospective cohort study حسب Salam Ibrahim Abou Safrah (21264303)

"…</p><h3>Conclusion</h3><p dir="ltr">There is no significant difference in the incidence of bleeding or VTE between the reduced dose and the standard dose of enoxaparin for VTE prophylaxis in underweight adult patients. …"

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

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A comparative single-dose bioequivalence study of two Glibenclamide brands among healthy volunteers. (c2000) حسب Tannous, Elias Fouad

"…Furthermore, the difference between area under serum concentration-time curve (AUC) for the two products ( 390.86 ± 152.61 and 360.7 ± 160.21 ng hr Iml for A and B, respectively) was not statistically significant, with P > 0.05. …"
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene حسب Ammouri, A.H.

"…No statistically significant dependence of peak load on stretch rate was found. …"
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A comparative single-dose bioequivalence study of two enteric coated Aspirin brands among healthy volunteers. (c2001) حسب Zeitoun, Abeer Abbas

"…Moreover, there was no statistically significant difference with respect to peak serum concentration (The Cmax values for Aspicot® (23,66 ± 16,26 ~g / mL) and Aspirin Protect® (21.73 ± 11.33 ug / mL) or to corresponding peaks time (the Tmax values ( 4,92 ± 2.35 hours and 4,58 ± 1,5 1 hours for Aspicot® and Aspirin Protect® respectively), Furthermore, the difference between area under the serum concentration time curve for the two products (the AUC for Aspicot® (66,20 ± 42,90 ug / mL) and Aspirin Protect® (64,79 ± 38,02 ug / mL) was not statistically significant, with P > 0,05. …"
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Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro حسب Khalife, Rana

"…The reduction in proliferation was significantly dose- and time-dependent. After determining the best combination (40 µM thymoquinone and 0.6 µM topotecan), cell proteins were extracted after treatment, and the expression levels of B-cell lymphoma 2 and of its associated X protein, proteins p53 and p21, and caspase-9, caspase-3, and caspase-8 were studied by Western blot. …"
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A comprehensive design and rating study of evaporative coolers and condensers. Part I. Performance evaluation حسب QURESHI, BILAL AHMED

"…It is demonstrated that thermal effectiveness of the evaporative heat exchangers degrades significantly with time indicating that, for a low risk level (pZ0.01), there is about 66.7% decrease in effectiveness for the given fouling model. …"
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Effect of high dose vitamin D supplementation on indices of sarcopenia and obesity assessed by DXA among older adults: A randomized controlled trial حسب Jabbour, Jana

"…Similarly, no significant differences were noted in the proportion of patients with SO at study entry (1.8% in LDG vs 1.6% HDG; p = 0.99) and at 12 months (3.7% in LDG vs. 0.9% HDG; p = 0.18) across arms. …"
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Assessment of four dose calculation algorithms using IAEA-TECDOC-1583 with medium dependency correction factor (K_med) application حسب Aram Rostami (22045274)

"…</p><h3>Conclusions</h3><p dir="ltr">This study highlights the significant impact of applying K_med on dose differences between measurement and calculation during the dose audit process.…"

Dosage, time, and polytherapy dependent effects of different levetiracetam regimens on cognitive function حسب Jon Davis Perkins (17885747)

"…</p><h3>Significance</h3><p dir="ltr">When taken in small doses, for brief periods as monotherapy, levetiracetam minimally influences cognition.…"

Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser حسب Salem, Hayder

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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy حسب Palavecino, Martin

"…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …"
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Pharmacokinetics of single‐dose rivaroxaban under fed state in obese vs. non‐obese subjects: An open‐label controlled clinical trial (RIVOBESE‐PK) حسب Majdoleen Alalawneh (13961580)

"…Rivaroxaban's exposure was similar between the obese and non‐obese subjects, and there were no significant differences in other pharmacokinetic parameters between the two groups. …"