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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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TIDCS: A Dynamic Intrusion Detection and Classification System Based Feature Selection
منشور في 2020"…TIDCS reduces the number of features in the input data based on a new algorithm for feature selection. Initially, the features are grouped randomly to increase the probability of making them participating in the generation of different groups, and sorted based on their accuracy scores. …"
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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …"
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Comparative evaluation of Dy(III) selective poly(vinyl) chloride based membrane electrodes of macrocyclic tetraimine Schiff’s bases
منشور في 2009"…Three different derivatives of macrocyclic tetraimine Schiff’s base have been synthesized and explored as a neutral ionophores for preparing poly(vinyl chloride) based membrane sensors selective to Dy3+. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Research Based Pedagogy to Enhance Quality of Learning: A Study Among Selected Higher Education Institutions in the UAE
منشور في 2024"…Research Based Pedagogy is referred to as a significant concept that would facilitate in creating research culture and to graduate students with high cognitive thinking order. …"
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An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems
منشور في 2024"…Feature selection (FS) is the activity of defining the most contributing feature subset among all used features to improve the superiority of datasets with a large number of dimensions by selecting significant features and eliminating redundant and irrelevant ones. …"
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Forecasting model to predict project success based on the contractors’ characteristics
منشور في 2018احصل على النص الكامل
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Nested ensemble selection: An effective hybrid feature selection method
منشور في 2023"…To address this issue, we propose a highly effective approach, called Nested Ensemble Selection (NES), that is based on a combination of filter and wrapper methods. …"
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Hemodynamics of small aneurysm pairs at the internal carotid artery
منشور في 2012"…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…"
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
منشور في 2006احصل على النص الكامل
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Enhancing fairness and scalability in IOTA tangle networks: a POMDP-based tip selection algorithm for decentralized systems
منشور في 2025"…This study presents a novel Partially Observable Markov Decision Process (POMDP)-based Tip Selection Algorithm (TSA) to optimize fairness in the IOTA Tangle. …"
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Low-Complexity Machine Learning-based Behavioral Modeling of Power Amplifiers
منشور في 2025احصل على النص الكامل
doctoralThesis -
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