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Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study
منشور في 2022"…Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. Therefore, this study aimed to evaluate the prevalence and clinical significance of aPLs among critically ill patients with COVID-19. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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All-terrain vehicle (ATV)-related injuries among different age groups: insights from a 9-year observational study
منشور في 2022"…There were no statistically significant differences regarding the use of protective devices, mortality, or length of hospital stay between the different age groups. …"
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. …"
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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
منشور في 2016"…There were significant differences between the groups in postoperative histology, with an increase in pathological stage III and TRG 4–5 in the R1 group. …"
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Hedonic valuation of land protection methods: implications for cluster development.
منشور في 2014"…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …"
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Ethnic and gender differences in the use of DISCOVER
منشور في 2009"…The purpose of this study was to examine ethnic and gender differences in using DISCOVER, a performance-based assessment, for identifying gifted students from diverse ethnicities. …"
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Clozapine prescribing practice and trends in Qatar: First national observational study
منشور في 2022"…Prescription rates were significantly different for Qatari patients when compared to non-Qatari patients. …"
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
منشور في 2022"…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. The LSB substitution method can minimize the error rate in embedding process and can achieve greater reliability in criteria, using novel algorithm based on value difference. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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The predictors of perforated appendicitis in the pediatric emergency department: A retrospective observational cohort study
منشور في 2021"…Objective Appendiceal perforation has significant effects on perioperative morbidity and postoperative outcome. …"
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The predictors of perforated appendicitis in the pediatric emergency department: A retrospective observational cohort study
منشور في 2021"…<h3>Objective</h3><p dir="ltr">Appendiceal perforation has significant effects on perioperative morbidity and postoperative outcome. …"
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…Upon rechallenge, in the animal group that had received WP1066 via o.g., the median survival was 18 days (95% CI: 17, NA), which was significantly different compared to naïve animals challenged at the same time that had a median survival of 11 days (95% CI; 10, NA) (p<0.001); however, there were only 10% long-term survivors suggesting that treatment alone did not generate significant long-term protective immunity. …"
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