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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. …"
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Hedonic valuation of land protection methods: implications for cluster development.
منشور في 2014"…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"
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Influence of proton pump inhibitors on gastritis diagnosis and pathologic gastric changes
منشور في 2015"…The computerized medical database of these patients was reviewed retrospectively in order to assess whether the type of gastritis diagnosed (H. pylori vs non-H. pylori gastritis) is influenced by PPI exposure. …"
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What factors influence firm perceptions of labour market constraints to growth in the MENA region?
منشور في 2015"…The authors also find significant heterogeneity in the factors’ implications for the perceptions of firms belonging to different sectors and located in different MENA countries. …"
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AI Integration Within the Architectural Design Process and Management, and its Influence on Project Agility: A Literature Review, Bibliometric, and Survey Analysis
منشور في 2024"…However, its effectiveness is influenced by organisational factors like the firm size, project complexity, and budget. …"
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
منشور في 2025"…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …"
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The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity
منشور في 2024"…Due to Hausman test significance, fixed effect estimation was used. The findings demonstrated a notable and favorable influence of board features, such as gender diversity, board independence, and board size, on European nonfinancial companies. …"
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
منشور في 2022"…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …"
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