يعرض 1 - 20 نتائج من 100 نتيجة بحث عن '(( significant ((spatial decrease) OR (substantial decrease)) ) OR ( significant genes decrease ))', وقت الاستعلام: 0.18s تنقيح النتائج
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    PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT حسب AHMED, AMIRA

    منشور في 2021
    "…Plasma glucose, leptin, and leptin gene expression (eWAT) were significantly reduced in the WT-DIO SFN treated group, while no changes were detected in KO mice. …"
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    INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR حسب ABDULKADER, HADIL

    منشور في 2024
    "…Circadian rhythms are maintained by a transcriptional auto-regulatory feedback loop including core clock genes. Evidence proposed the implication of the clock genes in obesity. …"
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    Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

    منشور في 2015
    "…The exposure of adipocytes to 1% hypoxia significantly alters the transcript of hypoxia genes, and other genes involved in glucose (GLUT1, GLUT4) and lipid (PPAR-γ) metabolism, and is also linked to anaerobic metabolism with apoptosis and increased oxidative stress. …"
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    Identification of key genes regulating macronutrient accumulation and final yield in wheat under potassium deficiency حسب Thabet, Samar G.

    منشور في 2024
    "…The wheat grains were analyzed for four macronutrients, mainly magnesium (Mg), calcium (Ca), potassium (K), and phosphorus (P), as well as yield attributes, under both treatments. A statistically significant decrease was observed for all assessed minerals and yield traits in wheat accessions under low potassium. …"
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    Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria حسب Al-Sadeq, Duaa W.

    منشور في 2024
    "…This reduced activity is consistent with both in vitro and in silico evidence, which indicates that the L230Q mutation significantly decreases the overall protein’s stability, which in turn, may represent the underlying cause of its pathogenicity.…"
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    Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: A systematic analysis from the Global Burden of Diseas... حسب Kendrick, Parkes J

    منشور في 2021
    "…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …"
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    Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Al-Amleh, Esraa K.

    منشور في 2022
    "…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
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    MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

    منشور في 2021
    "…This study investigated the differential gene expression of signaling pathways controlling TNBC CSCs. …"
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    Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

    منشور في 2019
    "…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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    STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS حسب AL-SADEQ, DUAA WALID

    منشور في 2024
    "…This reduced activity is consistent with both in vitro and in silico evidence, which indicates that the studied CBS mutations, except p.K72I, significantly decrease the overall protein's stability, which may represent the underlying cause of their pathogenicity. …"
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    Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

    منشور في 2018
    "…We searched 4 different literature databases (Google Scholar, PubMed, PubMed Central, and Science Direct) and 3 gene-variant databases (Online Mendelian Inheritance in Man, Human Gene Mutation Database, and UniProt) to collect all the reported missense mutations associated with GALK deficiency. …"
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    Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

    منشور في 2018
    "…Findings show that Sitg (50 mg) resulted in significant decrease in IS and DPP-4 activity, and significant increase in GLP-1, NOS activity, e-NOS expression, TRPV-1 level and TRPC-1 expression, compared to controls. …"
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