Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

"…<h3>Background</h3><p dir="ltr">Biological networks contribute effectively to unveil the complex structure of molecular interactions and to discover driver genes especially in cancer context. …"

Integrating Genome Sequencing and Untargeted Metabolomics in Monozygotic Twins with a Rare Complex Neurological Disorder حسب Rulan Shaath (17112852)

"…<p dir="ltr">Multi-omics approaches, which integrate genomics, transcriptomics, proteomics, and metabolomics, have emerged as powerful tools in the diagnosis of rare diseases. We used untargeted metabolomics and whole-genome sequencing (WGS) to gain a more comprehensive understanding of a rare disease with a complex presentation affecting female twins from a consanguineous family. …"

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration حسب Megan F. Duffy (5713772)

"…<h3>Background</h3><p dir="ltr">Converging evidence suggests a role for microglia-mediated neuroinflammation in Parkinson’s disease (PD). Animal models of PD can serve as a platform to investigate the role of neuroinflammation in degeneration in PD. …"

A complex presentation of an uncommon disease: Gas-forming pyogenic liver abscess complicated by septic pulmonary emboli and muscle abscesses, a case report and review of the liter... حسب Aseel H. Alzibdeh (17317009)

Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction حسب Daniel E. Platt (13982757)

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene حسب Zalloua, Pierre

"…Type 1 diabetes (T1D) is a complex autoimmune disease. Several genetic loci have been implicated in the susceptibility to this illness. …"
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

"…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …"

Qatar Health 2023: Showcasing how we emerged from navigating two storms حسب Guillaume Alinier (6952004)

"…The 2023 conference theme was “Clinical and Public Health Advances and Updates in Managing Complex Diseases”. The last few years have been extremely intense for everyone around the world, whether we consider the general population or healthcare professionals and support staff, dealing with and recovering from the COVID-19 pandemic. …"

Deciphering the complex interplay of obesity, epithelial barrier dysfunction, and tight junction remodeling: Unraveling potential therapeutic avenues حسب Sara K. AlMarzooqi (18767743)

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone حسب Ilhame Diboun (3522413)

"…Additionally, methylation profiles in 11 regions showed Bonferroni-significant association with disease severity including six islands (located in VCL, TBX5, CASZ1, ULBP2, NUDT15 and SQSTM1), two gene bodies (CXCR6 and DENND1A), and 3 promoter regions (RPL27, LINC00301 and VPS29). …"

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases حسب Mazhar Pasha (11197767)

"…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…"

The Use of Modified Composite Zeolite as A Novel Approach to Dental Hygiene Formulation حسب Rahman, Sumaita

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Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease حسب Sudharsana Sundarrajan (3181371)

"…<p dir="ltr">Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. …"

Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity حسب Rukaya Basala

"…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"

Advances in Huntington’s Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review حسب Sarah Aqel (17787809)

"…Given the complex pathology of HD, biomarkers are essential for performing early diagnosis, monitoring disease progression, and evaluating treatment efficacy. …"

ALOX5AP gene variants show differential association with coronary artery disease in different populations حسب Alwan, Ahmad

"…Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. …"
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Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study حسب Jonas Ellegaard Nielsen (21633062)

"…<h3>Introduction</h3><p dir="ltr">Alzheimer’s Disease (AD) is complex and novel approaches are urgently needed to aid in diagnosis. …"

Spectrum of genetic variants associated with maple syrup urine disease in the Middle East, North Africa, and Türkiye (MENAT): a systematic review حسب Salma Younes (6424865)

"…<h3>Background</h3><p dir="ltr">Maple syrup urine disease (MSUD) is a hereditary metabolic disorder caused by a deficiency in the branched-chain α-keto acid dehydrogenase (BCKD) enzymatic complex. …"

Preparation of Mesoporous/Microporous MnCo₂O₄ and Nanocubic MnCr₂O₄ Using a Single Step Solution Combustion Synthesis for Bifunction Oxy... حسب Anchu Ashok (14152020)