Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods حسب Charbel Al Khoury (13167975)

"…Consequently, resistant pests reduce the yield of agricultural production, causing significant economic losses and reducing food security. …"

Coevolving residues distant from the ligand binding site are involved in GAF domain function حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Ligand binding to GAF domains regulates the activity of associated catalytic domains in various proteins, such as the cGMP-hydrolyzing catalytic domain of phosphodiesterase 5 (PDE5) activated by cGMP binding to GAFa domain. …"

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... حسب Bogachev, Oleg

"…Macrophages from ApoE⁻′⁻/TG-BM chimeric mice express reduced levels of PPARγ₁, LXRα, ATP-binding cassette A₁ (ABCA₁) and ATP-binding cassette G₁ (ABCG₁) and increased levels of the inflammatory mediators interleukin (IL)-6 and tumor necrosis factor (TNF)-α compared with macrophages of control chimeric mice (ApoE⁻′⁻/NT-BM) that received AEBP₁ nontransgenic (AEBP₁ᴺᵀ) BM cells. …"
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model حسب Sahar Isa Da’as (18288880)

"…Although cardiac contractility was similar to the wild-type control, the ejection fraction was significantly increased in the mypbc3 mutants. At later stages of larval development, the mutants demonstrated an early cardiac phenotype of myocardium remodeling, concurrent cardiomyocyte hyperplasia, and increased ejection fraction as critical processes in HCM initiation to counteract the increased ventricular myocardial wall stress. …"

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

"…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …"

Downregulation of Lymphoid enhancer‐binding factor 1 (<i>LEF‐1)</i> expression (by immunohistochemistry and/ flow cytometry) in chronic Lymphocytic Leukemia with atypical immunophe... حسب Dina S. Soliman (14779333)

"…<h3>Introduction</h3><p dir="ltr">Lymphoid enhancer-binding factor 1 (<i>LEF-1</i>) overexpression has been recently remarkably reported in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and has shown utility in distinguishing CLL/SLL from other B-cell lymphomas. …"

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort حسب Muneerah Smith (12542939)

Preparation of Mesoporous/Microporous MnCo₂O₄ and Nanocubic MnCr₂O₄ Using a Single Step Solution Combustion Synthesis for Bifunction Oxy... حسب Anchu Ashok (14152020)

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function حسب Sahar I. Da'as (17128747)

"…Expression of CaM^D132E and CaMD134H mutants results in significant reduction of the zebrafish heart rate, mimicking a severe form of human bradycardia, whereas expression of CaM^Q136P results in an increased heart rate mimicking human ventricular tachycardia. …"

A novel hybrid methodology for fault diagnosis of wind energy conversion systems حسب Khaled Dhibi (16891524)

"…Feature selection pre-processing is an important step to increase the accuracy of the classification algorithm and decrease the dimensionality of a dataset. …"

A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems حسب Raka Jovanovic (17947838)

"…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …"

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

"…This was associated with an alteration in the expression levels of inflammatory factors in addition to an increase in the expression of the ER stress protein markers, namely immunoglobulin-binding protein (BiP), C/EBP homologous protein (CHOP), activation transcription factor 4 (ATF4), and X-box binding protein (XBP1). …"
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A decision support system for automating document retrieval and citation screening حسب Raymon van Dinter (10521952)

"…The proposed DSS is effective and can substantially decrease the document retrieval and citation screening steps' workload and error rate.…"

Minimizing Traffic Congestion through V2V Communication حسب Alqawasmeh, Suhieb

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A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle حسب Sanjay Kumar (8853)

"…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …"

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…Specifically, the N501Y mutation in the S1 spike receptor binding domain (S1-RBD) of these variants have been reported to increase its affinity for ACE2, although the basis for this is not entirely clear yet. …"

Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis حسب Susie S. Y. Huang (2824502)

"…Septic stimulation induced a significant increase in ERLIN1 expression; however, ERLIN1 was differentially expressed among the immune blood cell subsets. …"

Initial risk assessment for pulmonary hypertension in patients with COPD حسب Yammine, Joe

"…Diffusion capacity was lower but did not reach statistical significance (P = 0.07). In multivariate analysis, statistically significant independent variables were >3% decrease in exercise oxyhemoglobin saturation and decline in prebronchodilator FEV1 (P = 0.01 and P = 0.04, respectively). …"
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Use of Ultrasound and Ionic Liquids to Enhance the Extractive Desulfurization of Oils حسب Zuraiqi, Karma

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Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Advanced characterization revealed significant surface modifications, with Scanning Electron Microscopy (SEM) showing increased surface roughness, Fourier Transform Infrared Spectroscopy (FTIR) indicating involvement of hydroxyl, protein, and carbohydrate functional groups, and X-ray Photoelectron Spectroscopy (XPS) confirming Hg(II) binding to oxygen-containing moieties with distinctive Hg 4f peaks at 101.78 and 105.8 eV. …"