The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

Treating Cancers Using Nature’s Medicine: Significance and Challenges حسب Samson Samuel (6828956)

"…It is notable that an estimated 25–28% of modern medicines used by humanity, including those applied for the treatment of cancers, are directly or indirectly derivatives/compounds obtained from plants or other natural sources [3,4].…"

Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

"…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …"

Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients حسب Swapna Thomas (17337925)

"…Vaccinating diabetic patients against influenza would significantly reduce hospitalization due to disease severity. …"

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

"…At PACU, tramadol consumption per TBW and lean body mass (LBM) were significantly reduced in SMO (P = 0.001 and P = 0.025, respectively). …"

Bacteriuria in pregnancy varies with the ambiance: a retrospective observational study at a tertiary hospital in Doha, Qatar حسب Fathima Minisha (14585369)

"…<h3>Objectives</h3> <p>To explore the influence of ambient temperature and humidity on significant bacteriuria (SB) and urinary bacterial isolates in pregnant women.…"

The development of psychological and associated mental health disorders after road traffic crashes and other injuries حسب Anthony Joseph (3383735)

"…The main issue associated with the diagnosis and treatment of patients with PTSD and other psychiatric disorders depends on appropriate presentation and available treatment options including cognitive behavioural therapy, desensitisation or drug treatment. …"

Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline حسب Ramya Potabattula (4401160)

"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

The Development And Significance Of Business Intelligence (BI) Platforms In Facilitating The Decision-Making Process In Dubai Government Entities حسب ALMHEIRI, ABDULLA OBAID MOHAMMED

"…Thus, the current study has focused on analysing the significance of BI platforms in improving the decision-making process in the Dubai Statistics Center (DSC), a governmental entity in Dubai. …"
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Arnold-Chiari malformation and significant lumbar disc prolapse in pregnancy: A case report and literature review حسب Albert Adu Opoku (17280640)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…By elucidating a mechanistic basis for the increased affinity of the N501Y mutant S1-RBD for ACE2, we believe that the results presented here will aid in developing therapeutic strategies against SARS-CoV-2 including designing of therapeutic agents targeting the ACE2-S1-RBD interaction.…"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

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Sugar-Sweetened Beverages Contribute Significantly to College Students’ Daily Caloric Intake in Jordan: Soft Drinks Are Not the Major Contributor حسب Hiba Bawadi (3436379)

"…Anthropometric measurements of the participants including body weight, height, and waist circumferences were recorded. …"

Y-Chromosome and mtDNA Genetics Reveal Significant Contrasts in Affinities of Modern Middle Eastern Populations with European and African Populations حسب Khazen, Georges

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Systemic Inflammation May Induce Cardiac Injury in COVID-19 Patients Including Children and Adolescents Without Underlying Cardiovascular Diseases: A Systematic Review حسب Arwa Saed Aldien (17302849)

"…Only 29 studies met our inclusion criteria and the majority of these studies demonstrated significantly elevated inflammatory and cardiac blood markers. …"