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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Interval-Valued Reduced Ensemble Learning Based Fault Detection and Diagnosis Techniques for Uncertain Grid-Connected PV Systems
منشور في 2022"…The IKPCA-EL techniques are addressed so that the features extraction and selection phases are performed using the IKPCA models and the sensitive and significant interval-valued characteristics are transmitted to the EL model for classification purposes. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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A Diffusion-Based Probabilistic Ultra-Short-Term Solar Power Prediction Using the Sky Image Sequences
منشور في 2025"…<p dir="ltr">The inherently unpredictable nature of solar power generation, primarily due to rapidly changing cloud cover, poses a significant challenge to the operation of solar-integrated energy systems. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention
منشور في 2023"…This study also found significant evidence for serial mediation by POS on PGST and its relationship with turnover intention. …"
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Performance Prediction Using Classification
منشور في 2019"…Interestingly the variance in the performance measure values are not very significant for some of the models and it can be concluded that early risk prediction can happen earlier in the semester when intervention and associated benefits of improving student performance is more probable.…"
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Variation of Shear Wave Velocity with SPT-N Values in the City of Sharjah
منشور في 2014احصل على النص الكامل
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Prediction of evaporation losses in wet cooling towers
منشور في 2020"…An empirical relation is developed on the basis of ASHRAE’s rule of thumb that is simple and accurate with a wide range of applicability. The predicted values are in good agreement with experimental data as well as predictions made by an accurate mathematical model.…"
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