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decrease » increase (توسيع البحث)
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decrease » increase (توسيع البحث)
increases » increase (توسيع البحث), increased (توسيع البحث)
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Investigating the acoustic release of doxorubicin from targeted micelles
منشور في 2013"…The results showed that the percent drug release increases as the power intensity of ultrasound increases. …"
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Characterizing the dynamics of climate and native desert plants in Qatar
منشور في 2024"…By analyzing Landsat satellite images from 1985 to 2022 and their relation to rainfall patterns, we found significant impacts of climatic variables on vegetation coverage, particularly after 1990. …"
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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment
منشور في 2020"…The amount of resin significantly impacts the deionization efficiency; more ions are removed as the amount of resin increases.…"
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
منشور في 2002"…Fasting plasma glucose concentrations were significantly increased in both alcohol-tested groups whereas fasting plasma insulin was significantly increased in the beer group and not affected in the whisky group. …"
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masterThesis -
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Secure Storage of Crypto Wallet Seed Phrase Using ECC and Splitting Technique
منشور في 2024"…It was concluded that it is only possible to hack a seed phrase if a significant portion of it is already known, but even this would require a significant amount of time and computational power.…"
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
منشور في 2020"…HuArgI (Co)-PEG5000 is a potential drug to target cancers that depend on exogenous sources of arginine and cannot synthesize their own. In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …"
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masterThesis -
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The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion
منشور في 2020"…Cells treated with LT showed a significant decrease in motility as seen in 2D time-lapse and wound healing assays. …"
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masterThesis -
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Modulation of gut microbiota: The effects of a fruits and vegetables supplement
منشور في 2022"…<p dir="ltr">The consumption of an optimal amount of fruits and vegetables is known to improve physical fitness and physiological body functions. …"
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A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies
منشور في 2022"…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…"