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advances » advanced (توسيع البحث)
include » includes (توسيع البحث), included (توسيع البحث)
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Treating Cancers Using Nature’s Medicine: Significance and Challenges
منشور في 2021"…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …"
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
منشور في 2025احصل على النص الكامل
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Advancing Sustainable Energy Transition Through Green Hydrogen Valleys
منشور في 2025"…This review offers a comprehensive analysis of current scientific literature and recent advancements in GHV implementation, focusing on critical areas including electrolysis technology, material compatibility, hydrogen transportation, and economic feasibility. …"
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Transforming Agricultural Food Waste Into Bioplastics: Methods, Potential, and Technological Advances
منشور في 2025"…<p dir="ltr">The improper disposal of agricultural food waste (AFW) and its associated plastic packaging significantly exacerbates environmental degradation, including pollution, greenhouse gas emissions, and loss of valuable resources, while imposing substantial economic burdens. …"
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Artificial Intelligence in rehabilitation: A narrative review on advancing patient care
منشور في 2025"…Evidence from current literature highlights how AI improves patient satisfaction, engagement, and clinical outcomes by fostering a stronger therapeutic alliance and promoting adherence to treatment plans. However, significant challenges remain, including data privacy concerns, clinician training gaps, and disparities in technology access. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Provision of spiritual care to advanced cancer patients by doctors and nurses in the Middle East
منشور في 2016"…Methods: We distributed the Religion and Spirituality in Cancer Care Study via the Middle East Cancer Consortium to physicians and nurses caring for advanced cancer patients. Survey items include how often respondents think members of their profession should provide spiritual care, how often they themselves do so in practice, and their perceived barriers to spiritual care provision. …"
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Exploring recent advances in carrageenan-based films for sustainable food packaging applications
منشور في 2025"…<p dir="ltr">The use of non-renewable plastic packaging poses significant environmental challenges. To address these issues, researchers are focused on developing sustainable packaging materials that are environmentally friendly alternatives. …"