-
1
-
2
-
3
-
4
-
5
Gender-based differences in the prevalence and types of adverse childhood experiences and their associations with psychological distress and perceived lack of safety among adolesce...
منشور في 2025"…<p dir="ltr">Adverse Childhood Experiences (ACEs) are detrimental to well-being, but gender-specific data in Arab countries is scarce. …"
-
6
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
-
7
Utilization of the evidence from studies with no events in meta-analyses of adverse events: an empirical investigation
منشور في 2022"…Systematic reviews published at present (2015-2020) tended to incorporate zero-events studies in meta-analyses than those published in the past (2008-2011), but the difference was not significant (proportion difference=−0.09, 95% CI −0.21 to 0.03, p = 0.12).…"
-
8
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
-
9
-
10
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
-
11
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
12
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
13
The Effect of Different Doses of Intravenous Dexmedetomidine on the Properties of Subarachnoid Blockade: A Systematic Review and Meta-Analysis
منشور في 2020"…We analyzed the duration of sensory and motor blockade and the related adverse effects in relation to different doses of IV dexmedetomidine.…"
-
14
Socio‐economic impact of solar cooking technologies on community kitchens under different climate conditions: A review
منشور في 2024"…Additionally, toxic particles including sulfur dioxide, carbon monoxide, and mercury are released leading to elevated levels of indoor air pollution, and adversely affecting the health of the inhabitants. …"
-
15
-
16
An integrative comparative study between ultrasound-guided regional anesthesia versus parenteral opioids alone for analgesia in emergency department patients with hip fractures: A...
منشور في 2022"…A subgroup analysis of adverse events showed no significant difference in nausea/vomiting and respiratory complications. …"
-
17
Safety and efficacy of ensifentrine in COPD: A systemic review and meta-analysis
منشور في 2024"…George's Respiratory Questionnaire-C (SGRQ-C) scores (LS mean difference: −1.92; 95 % CI: −3.28 to −0.55). Safety profiles were comparable between the ensifentrine and placebo groups, with no significant increase in treatment-emergent <u>adverse events</u> (TEAEs) (RR: 1.02; 95 % CI: 0.94–1.10). …"
-
18
-
19
A population study of clinically actionable genetic variation affecting drug response from the Middle East
منشور في 2022"…The allele frequencies of 1,320 variants in 703 genes affecting 299 drugs or class of drugs were significantly different between the Qatari population and other world populations. …"
-
20
Temporal Trends in the Outcomes of Percutaneous Coronary Intervention With Zotarolimus Eluting Stents Versus Everolimus Eluting Stents: A Meta‐Analysis of Randomized Controlled Tri...
منشور في 2024"…At short‐term follow‐up (<2 years), there were no significant differences between the two types of stents (all‐cause death, cardiac death, Major adverse cardiovascular events (MACE), target vessel myocardial infarction, definite or probable stent thrombosis or safety outcomes (target vessel revascularization, target lesion revascularization, target vessel failure, target lesion failure). …"