Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline حسب Ramya Potabattula (4401160)

"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. This positive correlation between sperm rDNA methylation and biological age is evolutionarily conserved among mammals with widely different life spans such as humans, marmoset, bovine, and mouse. …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Deep aging clocks: AI-powered strategies for biological age estimation حسب Luma Srour (22254409)

"…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …"

Effect of consanguinity on birth weight for gestational age in a developing country حسب Wakim, Gerard

"…After controlling for medical and sociodemographic covariates, the authors found a statistically significant negative association between consanguinity and birth weight at each gestational age. …"
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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

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Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

Aging Effects in Field-Compacted Dredged Material حسب Wazne, Mahmoud

"…The addition of SSF to the 100% DM resulted in significant pH buffering and in strength increases up to a factor of 2, as measured by the average cone penetrometer test (CPT) tip resistance. …"
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Perinatal factors impacting echocardiographic left ventricular measurement in small for gestational age infants: a prospective cohort study حسب Ibrahim Elmakaty (14614270)

"…<h2>Introduction</h2><p dir="ltr">Infants born small for gestational age (SGA) have an increased risk of developing various cardiovascular complications. …"

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant حسب Lei Zhang (38117)

Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults حسب Ezzeddine, Maha

"…Objective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"

Crisis Management and Crisis Communication in the Digital Age: The Impact of Social Media حسب Thomas, Agnel Rose

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Health Care Accessibility of Lebanese Working-Age Adults with Musculoskeletal Disability حسب Jaber, Amani

"…The diversity of the Lebanese society increased after the 1975-1990 civil war, the grapes of Wrath conflict and July 2006 war. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"

Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism حسب Ramya Potabattula (4401160)

"…<p dir="ltr">Children from old fathers carry an increased risk for autism spectrum (ASD) and other neurodevelopmental disorders, which may at least partially be mediated by paternal age effects on the sperm epigenome. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis حسب Ahmad R. Al-Qudimat (17337808)

"…In addition, a combination of other comorbidities and old age appears to increase the risk of mortality from COVID-19.…"