يعرض 1 - 20 نتائج من 757 نتيجة بحث عن '(( significant application range ) OR ( significant ((we decrease) OR (a decrease)) ))', وقت الاستعلام: 0.13s تنقيح النتائج
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    Wide Range Voltage Scaling Converter With Extended Duty and Low Voltage Stress for a DC Microgrid Applications حسب Md Samiullah (16888767)

    منشور في 2025
    "…<p dir="ltr">DC–DC converters hold immense importance due to their diverse applications, making it critical to design them in accordance with the demanding operational requirements. …"
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    Voltage Lift Switched Inductor Double Leg Converter With Extended Duty Ratio for DC Microgrid Application حسب Md Samiullah (16888767)

    منشور في 2021
    "…Double duty control offers flexibility in the selection of duty ratio for a particular output voltage and a significantly high gain is easily attained. The double duty ratio not only provides an extended range but also improves the efficiency and performance of the converter. …"
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    Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

    منشور في 2025
    "…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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    Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

    منشور في 2023
    "…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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    Novel Enzyme-Free Multifunctional Bentonite/Polypyrrole/Silver Nanocomposite Sensor for Hydrogen Peroxide Detection over a Wide pH Range حسب Khouloud Jlassi (2583832)

    منشور في 2019
    "…<p dir="ltr">Precise designs of low-cost and efficient catalysts for the detection of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) over wide ranges of pH are important in various environmental applications. …"
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    Enhanced computer vision applications with blockchain: A review of applications and opportunities حسب Najmath, Ottakath

    منشور في 2023
    "…These technologies find applications in various domains, ranging from biometric entry cards and high-security clearances to surveillance. …"
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    Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines حسب Mansour, Najwa

    منشور في 2018
    "…Complex 1 demonstrated only marginal activity in the dark; its cytotoxicity increased significantly upon photoactivation with a high phototoxicity index (PI = [IC50 dark]/[IC50 light]) ranging from 39.2‐fold in A549 to over 100‐fold in MDA‐MB‐231. …"
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    Potential Medical Applications of Chitooligosaccharides حسب Sukumaran Anil (14158935)

    منشور في 2022
    "…COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. …"
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    Recent Overviews in Functional Polymer Composites for Biomedical Applications حسب Moustafa Zagho (18059980)

    منشور في 2018
    "…<p dir="ltr">Composite materials are considered as an essential part of our daily life due to their outstanding properties and diverse applications. Polymer composites are a widespread class of composites, characterized by low cost, facile processing methods, and varied applications ranging from daily-use issues to highly complicated electronics and advanced medical combinations. …"