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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Optimal Group Formation in Dense Wi-Fi Direct Networks for Content Distribution
منشور في 2019"…The results reveal significant performance gains in terms of group formation time and network throughput. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Predicting the Heats of Fusion of Ionic Liquids via Group Contribution Modeling and Machine Learning
منشور في 2022احصل على النص الكامل
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Undergraduate nursing students' perceptions of active learning strategies: A focus group study
منشور في 2023"…Data collected from the discussions were transcribed and thematically analyzed and aligned with the Taxonomy of Significant Learning. Results Study results show that undergraduate nursing students affirm that the use of active learning strategies supports the acquisition of foundational understanding, application and integration of knowledge, caring about the learning process, learning to learn, and the human dimension of learning. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Cellulose-based materials for antimicrobial water treatment: functionalization strategies and applications
منشور في 2025"…Water contamination by pathogenic microorganisms poses a significant threat to public health and ecosystems, necessitating the development of sustainable and efficient water decontamination technologies. …"
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Formal Verification of a Security Protocol in Vehicular Communication
منشور في 2025احصل على النص الكامل
doctoralThesis -
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A critical overview of thin films coating technologies for energy applications
منشور في 2023"…Such techniques have their own significance to develop the energy efficiency devices. …"
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