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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Dual-attention Network for View-invariant Action Recognition
منشور في 2023"…The DANet is composed of relation-aware spatiotemporal self-attention and spatiotemporal cross-attention modules. …"
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The declarative–procedural knowledge of grammatical functions in higher education ESL contexts: Fiction and reality
منشور في 2023"…Together, the findings are anticipated to spark more research on grammatical function knowledge among university students in ESL contexts.…"
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Factors Influencing the Magnitude and Clinical Significance of Drug Interactions Between Azole Antifungals and Select Immunosuppressants
منشور في 2006"…By bringing similarities and differences among these agents and their potential interactions to clinicians’ attention, they can appreciate and apply these findings in a individualized patient approach rather than follow only the one-size-fits-all dosing recommendations suggested in many tertiary references. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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A hybrid 3D CNN-LSTM model with soft spatial attention mechanism for accurate hyperspectral image classification
منشور في 2025"…Ablation studies revealed that residual connections improve training stability, while the attention mechanism effectively reduces redundancy. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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“Determinants of Body Image Dissatisfaction among an LGBTQ community in Lebanon”
منشور في 2021"…In conclusion, these results call attention to body image concerns among sexual minorities and a need for more extensive research with regards to this topic.…"
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Prevalence of severe moral distress among healthcare providers in Saudi Arabia
منشور في 2019"…There was no statistically significant difference between men and women in terms of moral distress. …"
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Seat belt and mobile phone use among young adult drivers in the State of Qatar
منشور في 2015"…Overall seat belt use among drivers was reported at 51% “always”, 41% “sometimes”, and 8% “never”. …"
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The association of patient safety culture with intent to leave among Jordanian nurses: a cross-sectional study
منشور في 2023"…Patient safety culture is getting more attention from healthcare organizations worldwide, and Jordan is no exception. …"
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Levels and Correlates of Functional Cervical Cancer Literacy among Lebanese Women: A Cross-sectional Study
منشور في 2024"…Conclusion: In addition to a national vaccination program against HPV combined with cervical cancer screening, we recommend the inclusion of cervical cancer as a topic within sexuality education programs. Special attention should be given to women with limited FCCL and uninsured women of low socioeconomic status. …"
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