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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Deciphering the complex interplay of obesity, epithelial barrier dysfunction, and tight junction remodeling: Unraveling potential therapeutic avenues
منشور في 2024"…<div><p>Obesity stands as a formidable global health challenge, predisposing individuals to a plethora of chronic illnesses such as cardiovascular disease, diabetes, and cancer. A confluence of genetic polymorphisms, suboptimal dietary choices, and sedentary lifestyles significantly contribute to the elevated incidence of obesity. …"
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Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes
منشور في 2022"…The rapid advancement in next generation sequencing technology has allowed for analysis of the diverse nature of microbial communities present in the barrier organs and a determination of their role in the induction of allergic disease. …"
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Promising approaches for controlled pulmonary drug delivery
منشور في 2015"…“Much research needs to be done in order to enhance them [and] deliver drugs efficiently to treat not only lung diseases but also diseases in [other parts of] the body.”…"
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Revealing the Adoption Factors of Electric Vehicles in Dubai
منشور في 2024"…Electric vehicles (EVs) have gained interest in the last decades, as a significant amount of people in Dubai depend on private vehicles. …"
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The Relationship between Smoking Cessation and Health Insurance Coverage: An Analysis of Cost Saving and Health Outcomes
منشور في 2023"…The use of tobacco products remains a significant public health concern worldwide, with smoking being a leading cause of preventable death and disease. …"
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
منشور في 2025"…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …"
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Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line
منشور في 2020"…A key morphological feature of inflammatory bowel disease (IBD) is the loss of the barrier function of intestinal epithelial cells. …"
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Do near-bedtime usage of smartphones and problematic internet usage really impact sleep? A study based on objectively recorded usage data
منشور في 2023"…</p><h3> Results</h3><p dir="ltr">The multivariate linear regression showed that the increase in PIU (β = −0.231, p < 0.001) and smartphone usage two hours before sleep (β = −0.246, p < 0.001) led to decrease in sleep duration. Regarding sleep distraction, multivariate linear regression analysis revealed that two hours before sleep was a significant and positive predictor of sleep distraction (β = 0.197, p = 0.003), whereas PIU was not significant. …"
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Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon
منشور في 2019"…Background: Diabetes Mellitus is a chronic metabolic disease that affects 387 million people around the world. …"
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Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis
منشور في 2025"…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …"
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Predictive Power of Random Forests in Analyzing Risk Management in Islamic Banking
منشور في 2024"…Concerns related to terrorism financing and cybersecurity risks have also decreased due to the better enforcement of anti-money laundering regulations and investments in cybersecurity infrastructure and education. …"
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Internalized Stigma in Persons With Mental Illness in Qatar: A Cross-Sectional Study
منشور في 2021"…<p dir="ltr">Stigma impacts persons with mental illness (PWMI), their families and network of friends, the public and health care professionals. Stigma is a major barrier for PWMI to seeking treatment, which contributes to the burden of disease, disability, and mortality. …"
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Quality of life, Knowledge and Access to Treatment in Times of Economic crisis in Lebanon
منشور في 2023"…Background Multiple sclerosis (MS) is a degenerative disease of the central nervous system that can lead to lifelong disabilities, and thus, significantly impacts patient's quality of life. …"
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Development of a cancer metastasis-on-chip assay for high throughput drug screening
منشور في 2024"…Further experimental analysis showed that Imatinib enhanced endothelial barrier stability as measured by trans-endothelial electrical resistance and significantly reduced the trans-endothelial invasion activity of tumor cells. …"
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Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals
منشور في 2023"…Oncology nurses, having a direct significant contact with these patients, could be the first information source concerning food safety and play a pivotal role in reducing these risks. …"
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Indwelling pleural catheters in hepatic hydrothorax
منشور في 2019"…There were statistically significant decreases in both BMI and serum albumin levels following IPC placement. …"
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Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals
منشور في 2023"…Oncology nurses, having a direct significant contact with these patients, could be the first information source concerning food safety and play a pivotal role in reducing these risks.…"