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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The promise of tirzepatide: A narrative review of metabolic benefits
منشور في 2025"…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …"
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Estimating Economic and Environmental Benefits of Urban Trees in Desert Regions
منشور في 2020"…In addition, trees have other benefits including increasing property value, intercepting storm water runoff and saving energy needed for cooling of buildings in hot seasons. …"
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Mobile Energy Storage Systems for Benefit Maximization in Resilient Smart Grids
منشور في 2025احصل على النص الكامل
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Effects of information and communication technology on total-factor carbon emission efficiency and the health co-benefits
منشور في 2024"…The results suggest that ICT significantly and positively impacts the TFCEE. Specifically, for every 10 per cent increase in the internet development index, the TFCEE increases by 0.11 per cent. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Triple helix components supporting STEM education to increase future STEM careers in the United Arab Emirates
منشور في 2023"…Increasing communication between government schools, universities, and industry can benefit STEM education programs and STEM careers. …"
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Cost-Benefit Analysis of Antimicrobial Stewardship Program Maturity in Adult Surgical Ward Settings: A Retrospective Study in Qatar
منشور في 2024"…</p><h3> Results</h3><p dir="ltr">The study included 108 patients in the premature ASP period and 88 in the mature ASP period. There was an increase in total costs for DDDs and resource utilization, amounting to QAR 163,002. …"
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Perceptions of Science Teachers Regarding Instruction that Increase High School Students' Motivation to Learn Science in Al Ain City
منشور في 2023"…The current study was carried out to investigate the high school science teachers’ perceptions regarding instruction that increases high school students’ motivation to learn science in Al Ain City. …"
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Increasing consultant-level staffing as a proportion of overall physician coverage improves emergency department length of stay targets
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">At the study site, in models that adjusted for overall on-duty EP numbers as well as myriad other operational factors, increasing numbers of on-duty Consultants was associated with a statistically and operationally significant reduction in ED LOS.…"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases
منشور في 2010"…Background The optimal duration, safety, and benefit of preoperative chemotherapy in patients with colorectal liver metastases (CLM) are unclear. …"
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