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Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study
منشور في 2022"…<p>Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy. Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The impact of maternal care on child development
منشور في 2019"…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Gestational Diabetes in the Gulf Region: Streamlining care to optimise outcome
منشور في 2015"…Despite the emerging body of evidence indicating adverse maternal and perinatal risks related to GDM, significant variations exist globally regarding the key components of GDM care, particularly, screening, diagnosis and long term follow up. …"
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Clinical characteristics and outcomes of care in patients hospitalized with diabetic ketoacidosis
منشور في 2022"…</p><h3>Conclusion</h3><p dir="ltr">In this national cohort of patients hospitalized with DKA, those with T2DM had a 7-fold increase in inpatient mortality associated with older age and admission to the intensive care unit.…"
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Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases
منشور في 2006"…Conclusion Steatohepatitis is associated with an increased 90-day mortality after hepatic surgery. In patients with hepatic CRM, the chemotherapy regimen should be carefully considered because the risk of hepatotoxicity is significant.…"
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Health Care Accessibility of Lebanese Working-Age Adults with Musculoskeletal Disability
منشور في 2016"…This category is more vulnerable in terms of health status, and hence requires more health care. Objective. To our knowledge, the health care accessibility of Lebanese young adults with physical disabilities has not been yet explored. …"
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Provision of spiritual care to advanced cancer patients by doctors and nurses in the Middle East
منشور في 2016"…Only the third most commonly cited reason, lack of adequate training (55%), remained significant in the MVA (p = 0.004). Conclusions: Staff spiritual care provision in the Middle East is higher than in the US, but we still see a large gap between its desirability and its actual provision. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Impact of pharmacist-conducted anticoagulation patient education and telephone follow-up on transitions of care
منشور في 2021"…Conclusions Although pharmacist-conducted anticoagulation education did not appear to reduce bleeding or readmission rates at day 30, pharmacist education significantly increased patient communication with their providers in the early days post-discharge.…"
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Predictors of Pressure Injuries in a Critical Care Unit in Lebanon: Prevalence, Characteristics, and Associated Factors
منشور في 2018"…Multivariate analysis indicated that length of stay (β= −.110; P = .002), administration of vasopressors (β=−.266; P = .029), and total hours of hypotension (β=−.53; P = .041) were significant predictors of pressure injury. CONCLUSIONS: Vasopressor use, hypotension, and length of stay were associated with an increased likelihood of pressure injury in adults managed in an MSICU. …"
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The Experience of Palliative Care Nurses in Qatar During the Time of COVID-19: A Qualitative Study
منشور في 2023"…One of the many areas affected by this pandemic has been palliative care. Palliative care nurses were thrust into a world of chaos as they faced increasing numbers of patients who were in the process of dying.…"
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Factors affecting job satisfaction among acute care nurses working in rural and urban settings
منشور في 2020"…Participants (N=349) completed the Acute Care Nurses’ Job Satisfaction Scale and The Anticipated Turnover Scale. …"