Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"

Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline حسب Ramya Potabattula (4401160)

"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. This positive correlation between sperm rDNA methylation and biological age is evolutionarily conserved among mammals with widely different life spans such as humans, marmoset, bovine, and mouse. …"

Causes of Delay in Construction Projects in Oil and Gas Construction Industry حسب FANOUSSE, MARWA IMAD

"…Issues related to client performance included bureaucracy and late honouring of certificates. Secondary causes such as rework, the rate of productivity, dispute management and delay analysis were also found to have great significance. …"
احصل على النص الكامل

Potential Medical Applications of Chitooligosaccharides حسب Sukumaran Anil (14158935)

"…COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. …"

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The potential of technology in education. (c2016) حسب Zain, Farah

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... حسب Katherine R Paulson (8674293)

"…To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival.…"

Potentially inappropriate medications use in community-based aged patients: a cross-sectional study using 2012 Beers criteria حسب Kuyumjian, Yara-Mary

"…The factors associated with PIMs use were age, osteoporosis, Alzheimer/dementia, diabetes, and alcohol consumption. PIMs use increased significantly between Beers criteria 2003 and 2012 (Chi-squared test, P<0.001; McNemar’s test, P<0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Burnout increased among university students during the COVID-19 pandemic: a systematic review and meta-analysis حسب Amit Abraham (5534822)

Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms حسب ALBLOOSHI, ROUDHA KHALID ABDULLA

"…Implementing a 6KV surge protector for higher-wattage lights significantly reduced defect rates by 0.5%. This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …"
احصل على النص الكامل

Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system حسب Frank Schmidt (207186)

Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines حسب Mansour, Najwa

"…In conclusion, the Ru‐centered complex 1 could represent a potential photoactivatable chemotherapeutic drug that increases selectivity to tumors and offers alternative treatment in the light of increasing cisplatin resistance.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Harnessing Waste for Emission Cuts: the Anaerobic Digestion Potential in Qatar حسب Sophia Ghanimeh (17787575)

"…<p dir="ltr">The Gulf Cooperation Council (GCC) countries are on the verge of a significant shift in waste management, with governments increasingly focused on reforming the waste sector. …"

Differing endometrial expression of calcium modulating transient receptor potential channels حسب Maryam Ghavideldarestani (11862563)

Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes حسب Abu Saleh Md Moin (6189512)

"…PPBP and THBS1 tended to increase at hypoglycemia in both cohorts, though reached significance only in controls (p < 0.05), returning to BL levels post-hypoglycemia. …"

Nuancing the double and triple nexus: analyzing the potential for unintended, negative consequences حسب Logan Cochrane (7822049)

"…<p dir="ltr">International and national actors are increasingly calling for a double or triple nexus approach to humanitarian, development, and peace activities to improve the flexibility of programming, particularly in complex crises. …"

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"

Solving the Narrow Corridor Problem in Potential Field-Guided Autonomous Robots حسب Masoud, A.A.

"…In addition to eliminating the narrow corridor artifact, improving the quality of the trajectory, the suggested solution significantly increases the speed of the robot. Theoretical development along with simulation results are provided.…"
احصل على النص الكامل
احصل على النص الكامل

Numerical investigation of the potential of using hydrogen as an alternative fuel in an industrial burner حسب Rashed Al-ajmi (19932174)

"…Mass flow rate (MFR) adjustments and excess air variation significantly influenced emissions, with a 25% MFR increase reducing NOx to 2.8 × 10^-5, while higher excess air (e.g.,30%) raised NO_x under lean conditions. …"