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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…To assess the effect of kefir on cancer metastasis, wound‑healing and time‑lapse movies, in addition to collagen‑based invasion assay, were used. The results show that cell‑free fractions of kefir exhibit an anti‑proliferative effect on Caco‑2 and HT‑29 cells. …"
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2
Scaffold‑based 3D cell culture models in cancer research
منشور في 2024"…Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. …"
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3
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4
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…Furthermore, treatment of MDA-MB-231 cells with either fraction significantly reduced the level of phosphorylated Erk but did not show any effect on phosphorylated Akt. …"
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5
Asynchronous MMC based parallel SA schemes for multiobjective standard cell placement
منشور في 2006"…Lee (1996) and applied to standard-cell placement as presented in J. Chandy et al. (1997), The schemes are applied to solve the multi-objective standard cell placement problem using an inexpensive cluster-of-workstations environment. …"
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6
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications
منشور في 2024احصل على النص الكامل
doctoralThesis -
8
Single-cell protein production from purple non-sulphur bacteria-based wastewater treatment
منشور في 2022"…<p>Large-scale production of single-cell protein (SCP) has the potential not only to solve some of the food insecurity and water scarcity crises that plague a significant portion of our world today but also holds the promise to reduce the cost associated with the treatment of industrial and agricultural wastewater. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Novel Whole-Cell Inactivated Neisseria Gonorrhoeae Microparticles as Vaccine Formulation in Microneedle-Based Transdermal Immunization
منشور في 2018"…Here we report that whole-cell-based gonococcal microparticle vaccine loaded in dissolvable microneedles for transdermal administration induced significant increase in antigen-specific IgG antibody titers and antigen-specific CD4 and CD8 T lymphocytes in mice compared to gonococcal antigens in solution or empty microneedles. …"
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Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016)
منشور في 2016"…This study aims to find the most efficient Ru-based compounds on a set of 6 cell lines from different solid tumors. …"
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masterThesis -
12
Performance Optimization in Lead-Free Perovskite Solar Cell: A Comparative Approach
منشور في 2025"…<p dir="ltr">Perovskite solar cells (PSCs) technology posses potential among numerous solar cells due to their promising sustainable energy solutions. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
منشور في 2016"…Of the four free ligands tested (L-I, L-II, L-III and L-IV corresponding to Ru-I, Ru-II, Ru-III and Ru-IV, respectively), significant cytotoxic activity was detected in eight out of nine cell lines, only with L-I and L-II, (IC50 values in the low μM range for L-I and reaching the nM range for L-II). …"
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masterThesis -
18
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19
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