Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia حسب Shilpa Kuttikrishnan (3520079)

Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases حسب Yousef Yahia (19756989)

"…Liver enzyme and bilirubin levels were significantly higher in the advanced types. Preoperative diagnosis was achieved in 70% of patients, with MRCP and ERCP being the most effective diagnostic tools. …"

Thermal challenges in lithium-ion battery technology: Investigating performance and thermal stability حسب Kenza Maher (22803425)

"…However, ensuring the safety and reliability of these batteries in desert environments presents significant challenges due to high temperatures, pervasive dust, and limited cooling mechanisms. …"

Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution حسب Kashif Bilal (16896357)

Efficacy and safety of ibrutinib in central nervous system lymphoma: A systematic review and meta-analysis حسب Jaber H. Jaradat (21632849)

"…There were no significant differences in the efficacy of ibrutinib between CNSL subtypes.…"

The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review حسب Maria Benkhadra (19756941)

"…<p dir="ltr">Intermittent fasting (IF) has recently gained popularity due to its emerging benefits in reducing weight and improving metabolic health. Concurrently, novel agents (NAs) like venetoclax and Bruton tyrosine kinase inhibitors (BTKIs) have revolutionized the treatment of chronic lymphocytic leukemia (CLL). …"

FIP1L1- platelet-derived growth factor receptor A -positive chronic eosinophilic leukemia showing dramatic response to imatinib حسب Mohammad Abu-Tineh (14829313)

"…</p><h3>Conclusion</h3><p dir="ltr">This case indicates that in the era of Tyrosine Kinase inhibitors such as imatinib, the prognosis of Eosinophilia associated with <i>FIP1L1-PDGFRA</i> rearrangement has significantly improved And Prompt treatment with imatinib can lead to complete hematological response and resolution of any organ damage involved with this disease.…"

Multilayer Reversible Data Hiding Based on the Difference Expansion Method Using Multilevel Thresholding of Host Images Based on the Slime Mould Algorithm حسب Abu Zitar, Raed

"…In the DE-based RDH method, finding spaces that create less distortion in the marked image is a significant challenge, and has a high insertion capacity. …"
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden حسب Monika, Rawat

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The impact of water table fluctuation and salinity on LNAPL distribution and geochemical properties in the smear zone under completely anaerobic conditions حسب Reem Elfatih Ismail (14151663)

"…At the source zone, benzene and toluene reached their maximum concentration after 30 and 10 days for the stable and the fluctuating columns, respectively. Significant decrease in benzene and toluene concentrations occurred under the fluctuating water table. …"

Parallel multi-voltage power minimization in VLSI circuits. (c2013) حسب Younes, Rabih Halim

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Release of colloids in saturated porous media under transient hydro-chemical conditions: A pore-scale study حسب Safna Nishad (16932474)

"…<p dir="ltr">The deposition and consequent release of colloids pose a significant challenge to the environment, groundwater quality and human health. …"

Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet حسب Bassil, Maya

"…Group III also had better glucose tolerance following intraperitoneal glucose challenges. Additionally, the plant extract intake produced a significant improvement in serum HDL (34.4 ± 2.4 in GIII vs. 27.2 ± 1.9 mg/dl in controls) and HDL/LDL cholesterol ratio (2.79 ± 0.32 in GII and 3.02 ± 0.31 in GIII vs. 1.74 ± 0.18 in controls), as well as a decrease in abdominal fat. …"
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…<p>Tumor progression through immune evasion is a major challenge in cancer therapy. Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. …"

Extent and Mitigation of Financial Toxicity of Immune Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma حسب Nabil E. Omar (9545756)

"…<p dir="ltr">Advanced hepatocellular carcinoma (HCC) is a serious condition associated with significant morbidity and mortality. Over the past few decades, however, this has drastically changed, primarily attributed to the development of new treatments, including tyrosine-kinase inhibitors (TKIs), vascular endothelial growth factor (VEGF) inhibitors, and immune checkpoint inhibitors (ICIs). …"

Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection حسب Atiq ur Rehman (3044409)

"…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…"

IS security menace حسب Balozian, Puzant

"…Nevertheless, this manuscript challenges that notion and advances a stream of research that suggests increasing security measures may lead to decrease in user productivity, increased user mistrust in the IT department, increased user frustration, increased user technology avoidance, increased non-malicious volitional security violations and overall may lead to increased security risk, instead of decreasing it. …"
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm حسب Prabu Selvam (22330264)

"…<p dir="ltr">Surface defects in Printed Circuit Boards (PCBs), which arise during manufacturing, significantly impact product quality and directly influence equipment performance, stability and reliability. …"

A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein حسب Natalie Landeck (414147)

"…</p><h3>Results</h3><p dir="ltr">Using our newly established duplex assay we measured total and pS129 h-asyn in vitro showing that polo-like kinase 2 (PLK2) can phosphorylate asyn up to 41 % in HEK293 cells and in vivo the same kinase phosphorylated h-asyn up to 17 % in rat ventral midbrain neurons. …"

The downsides of information systems security policy compliance efforts حسب Balozian, Puzant

"…Nevertheless, this dissertation challenges that notion and advances a stream of research that suggests increasing security measures may lead to decrease in user productivity, increased user mistrust toward the IT department, increased user frustration, increased user technology avoidance, increased non-malicious volitional security violations and overall may lead to increased security risk, instead of decreasing it. …"
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