يعرض 1 - 20 نتائج من 388 نتيجة بحث عن '(( significant challenges posed ) OR ( significant ((i.e decrease) OR (we decrease)) ))', وقت الاستعلام: 0.11s تنقيح النتائج
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

    منشور في 2025
    "…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

    منشور في 2025
    "…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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    Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

    منشور في 2023
    "…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    Power System Stability With High Penetration of Renewable Energy Sources: Challenges, Assessment, and Mitigation Strategies حسب Jana Sheikh Ali (22392121)

    منشور في 2025
    "…<p dir="ltr">The incorporation of renewable energy sources (RESs) into power systems has significantly increased in recent years due to growing environmental, economic, and energy security concerns, posing new challenges for power system stability. …"
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    Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases حسب Yousef Yahia (19756989)

    منشور في 2024
    "…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.</p><h3>Methods</h3><p dir="ltr">This retrospective study aimed to review our institutional experience in diagnosing and managing MS over seven years and four months.…"
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    Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters حسب Lina Majed (7485380)

    منشور في 2024
    "…While metabolic, perceptual and spatiotemporal values were sensitive to the smallest change in speed (i.e., 0.5 km·h<sup>−1)</sup>, a significant increase in the rate of carbohydrate oxidation and decrease in % fat oxidation were only observed at speeds above PWS. …"
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    Evaluating the authenticity of ChatGPT responses: a study on text-matching capabilities حسب Ahmed M. Elkhatat (14152314)

    منشور في 2023
    "…Several strategies are proposed to address the challenges posed by AI integration in academic contexts; one probable solution is to promote self-transcendent ideals by implementing honor codes. …"
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    Impact of Disruptive Innovation on Business Performance: Mediating Role of Crisis Management and Resilience حسب ALYASI, BADR

    منشور في 2024
    "…The insights gained highlight the importance of banking institutions strategically positioning themselves so as to withstand the challenges posed by disruptions and to leverage them as catalysts for growth and innovation.…"
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    Teachers' Perceptions of the Role of Artificial Intelligence in Facilitating Inclusive Practices for Students with Special Educational Needs and Disabilities: A Case Study in a Pri... حسب BACHIR, HIBAH AHMAD

    منشور في 2025
    "…The integration of Artificial Intelligence (AI) in education has raised significant discussions about its role in supporting inclusive learning for students with Special Educational Needs and Disabilities (SEND). …"
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