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Examining the Deviation in Energy Saving Estimations Due to the Use of the Degree Days Method
منشور في 2022"…This is difficult to calculate as many aspects that impact a building’s energy consumption continuously change, including the weather. The Degree Days method is commonly used to help estimate the energy saving while the weather is changing. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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The influence of strategic leadership and planning on the successful implementation of organizational change
منشور في 2011"…In today’s contemporary business world, characterized by fierce competition and uncertainty, In order to remain competitive, organization must be all set to change. Further, it is significant to note that the influence of the far environment on the organization is irresistible, as such the changes in the external and internal environment tends to dictate the need for change. …"
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Navigating environmental stress: Climate change impacts on adults' mental health in the Middle East
منشور في 2025"…Those with a preparatory school education scored higher on climate change anxiety than those with a higher degree (F = 4.623, P < .001). …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The Role and Impact of Educational Leadership in Change Management to Improve the Quality of Education in a Private School in Dubai
منشور في 2022"…The data results showed that educational leadership's significant role in managing change drives outstanding academic performance in this private school. …"
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Snow runoff modelling in the upper Indus River Basin and its implication to energy water food nexus
منشور في 2024"…It is expected that climate change may adversely affect future hydropower generation capacity as a result of fluctuations in the magnitude, seasonality and hydrological extremes of the Indus River flow. …"
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Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
منشور في 2023"…The engagement was carried out through the answering of a questionnaire survey that reflects their perceptions about climate change adaptation, the built environment resilience qualities (RQs), and the degree of resilience of the existing built environment and their perceived capacities. …"
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Positional and dimensional temporomandibular joint osseous changes in patients treated with the forsus fatigue resistant device: a non-randomized clinical trial
منشور في 2025"…Moreover, the anterior wall inclination in the treatment group was reduced by 3.13 ± 10.77 degrees, compared to an increase of 2.95 ± 4.1 degrees in the control group (<i>P</i> = 0.003). …"
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
منشور في 2023"…Females who started smoking last year were 2.6‐fold more than males (<i>p</i>< 0.0001). We also noticed that there is a significant relationship between those who started smoking and are <18 years, living in a family consisting of seven members or more, being unemployed, having a diploma or bachelor's degree in a health‐related major, having no chronic illnesses, increasing of daily meals or night meals, almost daily sugar intake, starting to follow social media account concerning physical activity, exercising once or twice a week, and sleeping more hours per day since the beginning of the pandemic (<i>p</i> < 0.01).…"
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A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar
منشور في 2023"…Male to female ratio was almost 1:1. We found a significant decrease in the intake of vegetables, increases in the intake of soft drinks, fried food, fast food, and sweets, and a reduction in physical activity during schools’ closure compared to before. …"