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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…The ability to detect statistical relevant changes in the interaction patterns induced by the progression of the disease can lead to the discovery of novel relevant signatures. …"
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THE IMPLICATIONS OF CHANGE AND CONTINUITY IN GCC LEADERSHIPS ON STATE–BUSINESS ELITE RELATIONS: THE CASES OF SAUDI ARABIA AND KUWAIT
منشور في 2025"…<p dir="ltr">The changes and continuities in the policies of the Saudi and Kuwaiti leaderships since the onset of the ‘Arab Spring’ in 2011 have significantly influenced the nexus of relations between the state and business elites, a nexus which significantly affects the variation between the two rentier states’ diversification processes. …"
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Managing change process: A case study of a private school in Sharjah
منشور في 2016"…The significance of change process management increases as the modern world trends of education and learning require a change. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Three cases of chronic photodermatitis successfully treated with upadacitinib
منشور في 2025"…Here, we report three cases of chronic photodermatitis treated with upadacitinib, a selective Janus kinase 1 inhibitor, as monotherapy, which resulted in fast, significant and sustainable improvement of signs and symptoms, with a favourable safety and tolerability profile.…"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Vocal Changes in Patients With Polycystic Ovary Syndrome
منشور في 2011"…Purpose The purpose of this study is to look at the prevalence of vocal symptoms and acoustic changes in patients with polycystic ovary syndrome (PCOS). …"
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Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity
منشور في 2024"…Findings indicated significant metabolic shifts in severe Long-COVID-19 cases, mainly a marked drop in HDL-C levels and a doubled increase in ferritin levels and insulin resistance compared to the mild cases and controls. …"
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Muslim personal names in Urdu: structure, meaning, and change
منشور في 2023"…Our study further shows that while Indian Muslim names trace their origins to Arabic, the structure of their names differs significantly from Arabs and other Muslims especially those in southern India. …"
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The influence of strategic leadership and planning on the successful implementation of organizational change
منشور في 2011"…In today’s contemporary business world, characterized by fierce competition and uncertainty, In order to remain competitive, organization must be all set to change. Further, it is significant to note that the influence of the far environment on the organization is irresistible, as such the changes in the external and internal environment tends to dictate the need for change. …"
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