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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"
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Analyzing hydrodynamic changes in the Dubai Creek: a pre- and post-extension study
منشور في 2023احصل على النص الكامل
doctoralThesis -
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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The status of human rights in post-Arab Spring. (c2015)
منشور في 2015"…First, it assesses hypothetical claim of global human rights regime having played a critical role in catalyzing the equal rights movements in both countries. Second, it reviews post-revolution constitutional changes as well as global human rights development indicators in Tunisia and Egypt in order to determine the extent to which new global human rights principles have been imbedded in the new political foundations. …"
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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Essays on the effect of excess compensation and governance changes on firm value
منشور في 2012"…We document a noticeable reduction in CEO turnover in the post-SOX period. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
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Education in post War-Somalia:Developing an Integrated Thematic Model of History Curriculum for Secondary Schools
منشور في 2019"…Qualitative interviews revealed five themes that appeared to be characteristic of a meritorious curriculum: Relevancy, Powerful Knowledge, Cause and Consequences, Change and Continuity, and Difficult History. The finding enabled the development of an integrated thematic instructional model which can help to determine suggestions for the development of an integrated thematic curriculum designed to deliver a new content and narrative that seeks to develop social cohesion and reconciliation and reconstruct national identity in post-conflict Somalia. …"
احصل على النص الكامل
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Post-Brexit exchange rate volatility and its impact on UK exports to eurozone countries: a bounds testing approach
منشور في 2023"…Findings & value added: GARCH(1,1) was selected as the winning model and used to examine the volatility structure of the post-Brexit exchange rate, which revealed no significant change. …"
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احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
منشور في 2019"…Eighteen of 29 RYGB (62%) had short-term diabetes remission. Changes from pre- to post-surgery in 32 of 175 microRNAs were nominally significant (p < 0.05). …"
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