A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry حسب Isbaih, Sara Samir

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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

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Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways حسب William J. Young (18426897)

"…In contrast for QRS, connective tissue components and processes for cell growth and extracellular matrix interactions are significantly enriched. …"

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant حسب Lei Zhang (38117)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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Y-Chromosome and mtDNA Genetics Reveal Significant Contrasts in Affinities of Modern Middle Eastern Populations with European and African Populations حسب Khazen, Georges

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

Problematic internet usage: the impact of objectively Recorded and categorized usage time, emotional intelligence components and subjective happiness about usage حسب Sameha Alshakhsi (17032311)

"…Multiple linear regression analysis showed that happiness with phone usage (β = −.17), the actual usage of communication (β = .17), social media (β = .19) and gaming apps (β = .13), and trait EI component of self-control (β = −.28) were all significant predictors of PIU. …"

All-polyethylene versus metal-backed tibial components in total knee arthroplasty: a meta-analysis of randomized controlled trials حسب Aissam Elmhiregh (14150667)

"…</p><h3>Results</h3><p dir="ltr">A total of 14 RCTs with 1367 TKA were included with a mean age of – years and – years for all-polyethylene and metal-backed tibial components groups, respectively. …"

The inhibitory effect of the methanolic extracts of origanum syriacum and rosmarinus officinalis and their major components on the biofilm formation of clinical isolates of staphyl... حسب Harb, Reeda Shawkat

"…The 21 clinical isolates S. aureus, included in the study, were defined phenotypically and genotypically. …"
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The Effectiveness of School Leaders’ Professional Development Programs in Promoting the Components of Professional Learning Communities in Jordan Public Secondary Schools According... حسب ABDALLAH, RAMI

"…Furthermore, the perceptions of the teachers about the extent of practicing the characteristics of Professional Learning Communities illustrated the nonexistence of clear common goals, vision, values and mission for all educators at the school related to the students’ learning, disorganized collaboration among educators, the lack of collective inquiry, the absence of action orientation, teachers commitment to continuous improvement is weak, the randomness of results orientation within the public schools and the weakness of school’s leadership role in promoting some components of the professional learning community. In general, some results indicated to significant statistical differences related to the demographic differences among participants (regarding the effectiveness of school leaders’ Professional Development Programs in promoting the characteristics of Professional Learning Communities at Jordanian public secondary schools.…"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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