Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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Board changes and CEO turnover حسب Dah, Mustafa A.

"…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"

Vocal Changes in Patients With Polycystic Ovary Syndrome حسب Hannoun, Antoine

"…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …"
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Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016) حسب Farhat, Stephanie Roy

"…This study aims to find the most efficient Ru-based compounds on a set of 6 cell lines from different solid tumors. …"
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Essays on the effect of excess compensation and governance changes on firm value حسب Dah, Mustafa A.

"…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …"
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS حسب Anna Halama (545988)

"…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …"

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership حسب JASIM, ARIF FADHEL AHMED

"…Leaders’ capacity to think about abstract and complex ideas has long been acknowledged as essential to leadership tasks such as planning and analysis; however, because conceptualisation is often ambiguous and difficult to understand, many frameworks of leadership and change lack clarity on the actual significance of leaders’ conceptual skills when leading change. …"
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Swimming exercise improves short‐ and long‐term memories: Time‐course changes حسب Mahmoud A. Alomari (14780446)

"…In this investigation, changes in the spatial hippocampal memory following a time-course of swimming exercise training were examined. …"

Exploring urban growth–climate change–flood risk nexus in fast growing cities حسب Salah Basem Ajjur (14150967)

"…In addition, Doha witnessed various climatic changes with a notable increase in air temperature (+ 8.7%), a decrease in surface wind speed (− 19.5%), and a decrease in potential evapotranspiration losses (− 33.5%). …"

Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition حسب Bouclaous, Carmel

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Evaluation of light-activated Ru(II) prodrugs and their photoproducts as potential anti-cancer agents حسب Elias, Maria

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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study حسب Almu'atasim Khamees (11875640)

"…Most of our sample's smoker participants experienced a change in their smoking level mostly, an increase. …"

The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells حسب Fayad, Christelle

"…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …"
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Co-production of high density biomass and high-value compounds via two-stage cultivation of Chlorella vulgaris using light intensity and a combination of salt stressors حسب Eman A. El-fayoumy (17788952)

Novel Platinum II and Platinum IV Complexes Exhibit An Anti-Neoplastic Potential Against A549 Cancer Cell Line حسب Baz, Joy

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The anti-neoplastic activity of novel platinum II and IV complexes against A549 lung cancer cells حسب Al Sayegh, Rouba

"…Western blots experiments were also carried out to observe the effect of the drugs on key apoptotic proteins. Data revealed a significant drop in procaspase 3 and a significant increase in Bax/Bcl2 ratio, Cytochrome c, Parp and procaspase 8. …"
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m² 21 days postoperatively. …"