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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Growth hormone treatment modulates active ghrelin levels in rats
منشور في 2014"…Genotropin treatment caused a dose dependent decrease in active ghrelin concentration in stomach, kidney and pancreas with a concomitant increase in plasma, and reaching significance at 20 and 100 µg/rat/day doses. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
منشور في 2020"…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …"
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…Furthermore, treatment with AuNPs caused significant alterations in cholesterol ester levels, essential for lipid storage and transport, indicating disruptions in these mechanisms. …"
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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
منشور في 2019"…Paired <i>t-</i>test analysis of 22 locally advanced breast cancer patients showed that plasma NRP-1 levels were increased significantly (<i>p</i> = 0.018) post-NAC in patients with pathological partial response (pPR). …"
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
منشور في 2017"…After accounting for the role of coal as a baseload power source, an increase in the share of renewable energy is estimated to mitigate N2O emissions at the U.S. state level only if states individually decrease their share of coal use to levels below 41.47%. …"
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Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
منشور في 2021"…The results revealed that the new tool is beneficial, and the median times to finish the processes within the patient’s journey have significantly decreased. To evaluate the use of the enhanced QMS, this research develops an integrated model based on the integration of various constructs extracted from different theoretical models, including the UTAUT, TAM, and social cognitive theory (SCT) along with trust and innovativeness as external factors. …"
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11
Stress Management Using Physiological Signals and Audio Stimulation
منشور في 2021احصل على النص الكامل
doctoralThesis -
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Processing Effects on the Oxytetracycline and Tylosin Antibiotic Residues in Middle Eastern Dairy Products
منشور في 2020"…OTC and TYL were not homogenously distributed between the dairy products. Skimming decreased significantly (p=0.015) TYL concentration by 68.6%. …"
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masterThesis -
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Non-diabetic ketoacidosis secondary to primary hyperthyroidism
منشور في 2022"…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …"
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The chemical analysis of Lebanese olive oil and the influence of oil enriched diet on Plasma Lipid profile in rats. (c2002)
منشور في 2002"…Following ten week low fat verses high fat diet, no significant difference was observed among the various groups in lipid profile, insulin and Apo B 100 & 48 levels. …"
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masterThesis -
15
Revealing the Adoption Factors of Electric Vehicles in Dubai
منشور في 2024"…Electric vehicles (EVs) have gained interest in the last decades, as a significant amount of people in Dubai depend on private vehicles. …"
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Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
منشور في 2021"…Dietary OTA at all the tested levels induced the hepatic and renal tissue injury as indicated by significant decreased total antioxidant capacity in these organs along with significant decreased (p ≤ 0.05) serum concentrations of total proteins and albumin. …"
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
منشور في 2002"…Neither IL-1 nor ceramide induced apoptosis in IEC, but they increased bcl-2 levels and decreased bax and p21 levels without affecting bcl-x and p53 levels. …"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…We characterized variants in <i>CCL5</i> and that of six other CCL5 signaling genes (<i>CCND1, ZMIZ1, CASP8, NOTCH2, MAP3K21, and HS6ST3</i>) among 1,082 unrelated Tunisian subjects (544 BC patients, including 196 TNBC, and 538 healthy controls), assessed the association of the variants with BC-specific overall survival (OVS) and progression-free survival (PFS), and correlated CCL5 mRNA and serum levels with <i>CCL5</i> genotypes. We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
منشور في 2018"…More interestingly, a 3-month physical exercise differentially affected HSP60 expression and the heat shock response but attenuated inflammation in both groups, as reflected by decreased endogenous levels of IL-6 and TNF-α. Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …"
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
منشور في 2018"…It also significantly decreased the levels of pro-caspase-3, p53, Bcl-2, p-Erk/Erk and p-Akt/Akt and increased p21 and Bax proteins. …"
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