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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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The impact of environment concern and attitude on green purchasing behavior
منشور في 2015"…The moderating effect of gender was found to be significant and affect both environmental concern and attitude towards green purchasing behavior. …"
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Towards a Conceptual Framework on the Importance of Privacy and Security Concerns in Audit Data Analytics
منشور في 2021"…Privacy and security concerns with Big Data have gained momentum in both research and business fields. …"
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conferenceObject -
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Airway surface liquid volume expansion induces rapid changes in amiloride-sensitive Na<sup>+</sup>transport across upper airway epithelium-Implications concerning the resolution of...
منشور في 2015"…We previously demonstrated that elevation of submucosal hydrostatic pressure increases airway epithelium permeability resulting in ASLV expansion by 500 μL cm<sup>−2</sup> h<sup>−1</sup>. …"
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HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
منشور في 2021"…<p dir="ltr">Diabetes mellitus is associated with increased risk of erectile dysfunction. Penile prosthesis implantation is an efficient therapeutic option for erectile dysfunction, but not without risk, as infection remains a prominent concern. …"
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Effects of Social Media Use and Dependence on Dietary Intake and Prevalence of Orthorexia in Pregnant and Non-Pregnant Women
منشور في 2022"…That being said, interventions to regulate social media content and limit exposure to unrealistic thin ideal as well as to educate women about dietary changes and requirements during pregnancy may be helpful to increase intuitive eating behaviors and decrease the risk of disordered eating and orthorexia in this population.…"
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Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions
منشور في 2017"…The Bingham yield stress, from the low shear rate data, increased linearly with temperature, while the plastic viscosity decreased with temperature, in a manner very similar to the decrease of water viscosity with temperature. …"
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Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
منشور في 2022"…In a multivariate logistic regression model, massive PE features significantly increased the odds of death (OR: 29.3, CI: 4.86–181.81, p < 0.001), whereas, treatment with anticoagulation (AC) alone (OR: 0.1, CI: 0.027–0.356, p < 0.001), TT (OR: 0.065, CI: 0.019–0.26, p < 0.001), surgical thrombectomy (ST) (OR: 0.047, CI: (0.010–0.23), p < 0.001), or percutaneous thrombectomy (PT) (OR: 0.12, CI: 0.020–0.84, p = 0.032) significantly decreased odds of death.…"
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
منشور في 2002"…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …"
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masterThesis -
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
منشور في 2015"…A significant increase in serum blood glucose level was observed with hydroxycut intake in the presence of a high-fat diet. …"
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article