Association between Healthy Lifestyle Index and Cognitive decline In Community- Dwelling Lebanese Older Adults حسب Ezzeddine, Maha

"…Objective: Normal aging is often associated with cognitive deterioration in older adults, but the prevalence of cognitive decline like cognitive impairment, Alzheimer’s disease and dementia has been increasing lately. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Lower limb EMG activation during reduced gravity running on an incline. Speed matters more than hills irrespective of indicated bodyweight حسب Rod Whiteley (14150088)

"…Increasing running speed was associated with the largest change in activity, with smaller effects for increasing bodyweight and inclination. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

"…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …"
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Prevalence and risk of cognitive impairment among patients with asthma: A systematic review and meta‐analysis حسب Ganesh Bushi (19709574)

"…The results underscored the substantial correlation between asthma and heightened risks of cognitive decline, dementia, and Alzheimer's disease.</p><h3>Conclusion</h3><p dir="ltr">This review found a notable association between asthma and an increased risk of cognitive decline, including dementia and Alzheimer's disease. …"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Esraa K. Al-Amleh (16023071)

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …"

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …"

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

Screen Time Soars and Vision Suffers: How School Closures During the Pandemic Affected Children and Adolescents’ Eyesight حسب Muna Abed Alah (18336771)

"…Furthermore, logistic regression analysis showed that local students and those with a history of visual disturbances were 1.7 times (AOR: 1.73, 95%CI 1.18–2.54, <i>p</i> = 0.005) and 2.5 times (AOR: 2.52, 95%CI 1.69–3.76, <i>p</i> < 0.001) more likely to experience decline of visual acuity respectively. School closures in Qatar were associated with a significant increase in screen time among students and a notable decline in their visual acuity. …"

Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease حسب Ramadan, Wijdan H.

"…For patients not sufficiently controlled on a single long-acting bronchodilator, a combination of different bronchodilators has shown a significant increase in lung function. Tiotropium, a once-daily dosing LAMA, demonstrated sustained improvements in lung function as well as improved health-related quality of life, reduced exacerbations, and increased survival without altering the rate of decline in the mean forced expiratory volume in 1 second (FEV1) with fairly tolerable side effects. …"
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells حسب Ali Alhoshani (3720718)

"…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …"

Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …"
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Proteome analysis of Candida albicans cell wall mutants. (c2011) حسب Koussa, Joseph Wissam

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The Russia-Ukraine war, soaring food prices, and the Turkish economy: insights from computable general equilibrium حسب Ozcan Ozturk (14606326)

"…The findings reveal significant effects on agricultural imports of crops (wheat, maize, barley, rice, and cereal grains), fruit and vegetables, and oil products, leading to an increase in both import and domestic prices, resulting in food inflation in the country. …"

Characteristics of aerosols and planetary boundary layer dynamics during biomass burning season حسب Muhammad Zeeshaan Shahid (18131689)

"…The results illustrate the key contributors to this haze event and showed the there is significant increases in aerosol components such as sulfate, black carbon, organic carbon, dust and aerosol optical depth (AOD). …"

Mixed matrix membranes containing aspartic acid functionalized graphene oxide for enhanced oil-water emulsion separation حسب Omnya Abdalla (17100211)

"…Water permeability increased by 97 % at 0.2 wt.% fGO membrane compared to pristine membrane and oil rejection reached 97.9 % upon filtration of 200 mL oil emulsion. …"