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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis
منشور في 2022"…<h3>Objective</h3><p dir="ltr">The main aim is to compare the risk of severe hypoglycemia associated with the modified-release (MR) gliclazide against glimepiride in diabetic older adults. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Ultrasound Triggered Release of Estrone- Targeted Liposomes
منشور في 2017احصل على النص الكامل
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Investigating the acoustic release of doxorubicin from targeted micelles
منشور في 2013"…We applied low frequency ultrasound as an external stimulus and measured the amount of release of Dox from these folated micelles. The results showed that the percent drug release increases as the power intensity of ultrasound increases. …"
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Kinetics of ultrasonic release of doxorubicin from pluronic P105 micelles
منشور في 2001"…Above this threshold, the amount of release was shown to increase as the pulse length increased up to 0.6 s. …"
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
منشور في 2018احصل على النص الكامل
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Ultrasound-responsive Nanocarriers in Cancer Treatment: a review
منشور في 2021"…Using smart nanocarriers, the rate of release of the entrapped therapeutic(s) can be increased, and greater exposure of the tumor cells to the therapeutics can be achieved when the nanocarriers are exposed to certain internally (enzymes, pH and temperature) or externally applied (light, magnetic field, and ultrasound) stimuli that trigger the release of their load in a safe and controlled manner, spatially and temporally. …"
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
منشور في 2016احصل على النص الكامل
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Lacertus fibrosus release in proximal median nerve entrapment- a systematic review
منشور في 2025"…A significant proportion of the patients had a history of unsuccessful conservative or surgical management (prior carpal tunnel release in 10.5%). …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Accelerated dissolution testing for controlled release microspheres using the flow-through dissolution apparatus
منشور في 2008"…The effect of increased temperature was determined to be the statistically significant variable.…"
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احصل على النص الكامل
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