DNA Base-Calling Techniques حسب Odeh, Fadi

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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Analysis of DNA content by flow cytometry revealed the ability of kefir to induce cell cycle arrest at the G1 phase. …"
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Novel algorithms for accurate DNA base-calling حسب Mohammed, Omniyah Gul

"…The importance of DNA sequencing necessitated a need for efficient automation of identification of base sequences from traces generated by existing sequencing machines, a process referred to as DNA base-calling. …"
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Y-Chromosome and mtDNA Genetics Reveal Significant Contrasts in Affinities of Modern Middle Eastern Populations with European and African Populations حسب Khazen, Georges

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A New Restriction Endonuclease-Based Method for Highly-Specific Detection of DNA Targets from Methicillin-Resistant Staphylococcus aureus حسب Maria W. Smith (18807382)

"…We developed a new approach for analysis of PCR amplicons based on restriction endonuclease digestion. The first stage of the restriction enzyme assay is hybridization of a target DNA to immobilized complementary oligonucleotide probes that carry a molecular marker, horseradish peroxidase (HRP). …"

Zeolitic Imidazolate Framework-Based Biosensing Platform for Detection of Covid-19 RNA حسب Elgazar, Aya Tarek

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The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome حسب Kareim Khalafalla (14148807)

"…Based on sperm DNA fragmentation cut-off values, the patients were differentiated into 3 groups as <20%, 20%–30% and >30%. …"

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone حسب Ilhame Diboun (3522413)

"…</p><p><br></p><h3>Objectives: </h3><p dir="ltr">To investigate the association between DNA methylation signals and PDB severity.</p><p><br></p><h3>Methods: </h3><p dir="ltr">Using 232 well-characterized PDB subjects from the PRISM trial, a disease severity score was devised based on the clinical features of PDB. …"

Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease حسب El Maarri, Osman

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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor—An Opportunity for Cancer Treatment حسب Mohammad A. I. Al-Hatamleh (11564929)

"…This perspective review discusses a novel therapeutic strategy based on nanomedicine that has the capacity to target TNFR2 along with inhibition of DNA demethylation. …"

Evaluation of light-activated Ru(II) prodrugs and their photoproducts as potential anti-cancer agents حسب Elias, Maria

"…Cytotoxicity assays on A375 showed a mean phototoxicity index of 340 at 72 hours, presenting the intracellular aquated photoproducts being effective rather than the dissociating ligands. A significant increase in ROS production and DNA damage was also observed. …"
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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) حسب Khaled F. Alkaraki (22051967)

"…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …"

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene حسب Zalloua, Pierre

"…The GG genotype was also significantly higher among patients (12.6%) than in controls (4.2%). χ2 analysis and family-based association studies were performed and suggested the association of CTLA4 exon 1 G polymorphism with T1D (p = 0.0229). …"
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

"…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …"
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A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation حسب El Maarri, Osman

"…Association analysis between all major polymorphisms (frequency > 1%) and quantitative DNA methylation profiles did not return significant results after correction for multiple testing. …"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"