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يعرض 1 - 20 نتائج من 184 نتيجة بحث عن '(( significant drug based ) OR ( significant ((step decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.12s تنقيح النتائج
  1. 1

    Metal–Organic Framework-Based Drug Delivery Systems for Cancer Therapy: A Review حسب Hatami, Sedigheh

    منشور في 2026
    "…Cancer remains one of the most significant global health challenges, with conventional treatments limited by side effects and resistance to drugs. …"
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    article
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    Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles حسب Taleb, Robin I.

    منشور في 2007
    "…Encapsulation by CB[6] was found to not significantly change the cytotoxicity of five platinum(II)-based DNA intercalators, indicating it may have utility as a molecular carrier for improved drug delivery.…"
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    article
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    pH and ultrasound dual-responsive drug delivery system based on PEG–folate-functionalized Iron-based metal–organic framework for targeted doxorubicin delivery حسب Ahmed, Ahmed H.S

    منشور في 2021
    "…In this work, dual-responsive iron-based MOFs were synthesized via the microwave-assisted method using FeCl₃.6 (H₂O) as the metal cluster and 2-aminoterephthalic acid (NH₂-BDC) as the organic linker (namely NH₂-Fe-BDC) and loaded with the anti-cancer drug doxorubicin (DOX). …"
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    article
  6. 6

    Whole-genome sequencing based molecular characterization of multi-drug resistant isolates of Enterobacter spp. and Klebsiella aerogenes in Lebanon. (c2019) حسب Merhi, Georgi S.

    منشور في 2019
    "…They are commonly notorious for causing healthcare-associated infections and impose a significant burden on secondary health-centers. In the last few decades, the rise of ECC and K. aerogenes as successful nosocomial pathogens was paralleled by the global alarming emergence of multi-drug resistant clones of these bacteria. …"
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    masterThesis
  7. 7

    Promising approaches for controlled pulmonary drug delivery حسب Nature Research (16552612)

    منشور في 2015
    "…Micro- and nanoparticles-based drug delivery systems could potentially improve the delivery of inhaled drugs significantly, because they can be designed in specific shapes and sizes, and with certain other properties that optimize their bioavailability. …"
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    Efficacy and Safety of Colistin versus Tigecycline for Multi-Drug-Resistant and Extensively Drug-Resistant Gram-Negative Pathogens—A Meta-Analysis حسب Dina Abushanab (10696501)

    منشور في 2022
    "…<h3>Background</h3><p dir="ltr">We intended to compare the efficacy and safety outcomes of colistin versus tigecycline as monotherapy or combination therapy against multi-drug resistant (MDR) and extensively drug-resistant (XDR) pathogens. …"
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    Machine Learning Techniques for Pharmaceutical Bioinformatics حسب SULTAN, AHMED ATTA AHMED

    منشور في 2018
    "…The study integrates knowledge visualization, analysis, as well as development of a predictive model based on the Drug-Drug Interactions (DDIs) as a complex network. …"
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    Deep Learning for the Accurate Prediction of Triggered Drug Delivery حسب Husseini, Ghaleb

    منشور في 2024
    "…The deep learning-based predictions significantly outperform linear predictions, proving the utility of advanced computational methods in drug delivery. …"
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    article
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    High-amylose carboxymethyl starch matrices for oral sustained drug-release حسب Nabais, T.

    منشور في 2016
    "…Until now, their controlled-release properties have been assessed only by an in vitro dissolution test. Amylose-based polymers are normally subject to biodegradation by α-amylase enzymes present in the gastrointestinal tract, but matrix systems show no significant degradation of tablets by α-amylase in vitro. …"
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    article
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    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping حسب Karsten Suhre (67967)

    منشور في 2024
    "…<p dir="ltr">Proteogenomics studies generate hypotheses on protein function and provide genetic evidence for drug target prioritization. Most previous work has been conducted using affinity-based proteomics approaches. …"
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    Physicochemical studies of binary eutectic of ibuprofen and ketoprofen for enhanced transdermal drug delivery حسب Capomacchia, Anthony Cesare

    منشور في 2010
    "…The NSAID membrane flux values were calculated by flux ratio equations based on drug thermodynamic data, and compared to experimental values obtained from permeation studies. …"
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    article
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    Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

    منشور في 2019
    "…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …"
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    Plasma Bead Entrapped Liposomes as a Potential Drug Delivery System to Combat Fungal Infections حسب Munazza Tamkeen Fatima (17316955)

    منشور في 2022
    "…<div><p>Fibrin-based systems offer promises in drug and gene delivery as well as tissue engineering. …"
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    Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

    منشور في 2021
    "…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
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    article
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    Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing? حسب Athar Khalil (5906330)

    منشور في 2020
    "…Yet, the absence of substantial evidence on Thalidomide usage in that context along with the discontinued studies on the efficiency of this drug in similar pulmonary diseases, might cause a significant obstacle for carrying out further clinical evaluations. …"