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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake
منشور في 2002"…The effect of high-frequency ultrasound on doxorubicin (DOX) release from Pluronic micelles and intracellular DOX uptake was studied for promyelocytic leukemia HL-60 cells, ovarian carcinoma drug-sensitive and multidrug-resistant (MDR) cells (A2780 and A2780/ADR, respectively), and breast cancer MCF-7 cells. …"
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Ultrasound Triggered Release of Estrone- Targeted Liposomes
منشور في 2017احصل على النص الكامل
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Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study
منشور في 2021"…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. All the patients in the study group had a reduction of >6 points in the NIH-CPSI score, indicating a robust treatment response. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Investigating the acoustic release of doxorubicin from targeted micelles
منشور في 2013"…The maximum amount of release (14%) was measured at 5.4 W/cm². A power density threshold at approximately 0.55 W/cm² exists below which no statistically significant release was observed. …"
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Encapsulation and Release of Calcein from Herceptin-conjugated eLiposomes
منشور في 2023احصل على النص الكامل
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Light-Responsive Metal-Organic Frameworks (MOFs) For Doxorubicin Controlled Release
منشور في 2023احصل على النص الكامل
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The Effect of Ultrasound on the Drug Delivery of RGD-Targeted Liposomes
منشور في 2018احصل على النص الكامل
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
منشور في 2018احصل على النص الكامل
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Ultrasound-responsive Nanocarriers in Cancer Treatment: a review
منشور في 2021"…The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. …"
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
منشور في 2016احصل على النص الكامل
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Dynamics of Chemotherapeutic Drug Release from Liposomes Using Low-Frequency Ultrasound
منشور في 2015احصل على النص الكامل
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"