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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The effectiveness of physical models in teaching anatomy
منشور في 2016"…The aim of this meta-analysis is to quantitatively assess the effectiveness of such models based on comparative studies. …"
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Detection of statistically significant network changes in complex biological networks
منشور في 2017"…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Contagion effects in a chartist–fundamentalist model with time delays
منشور في 2007"…In this paper two models of speculative markets are developed to study the effects of feedback mechanisms in financial markets. …"
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Effects of BIM in Enhancing Prefabricated Construction
منشور في 2021احصل على النص الكامل
doctoralThesis -
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Non-Newtonian Effects in a Fluid-Structure Interaction Model for Atherosclerosis
منشور في 2009"…The simulations show that the Newtonian model significantly overestimates the recirculations in comparison with the non-Newtonian model. …"
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
منشور في 2011"…The concept of staff professional development and its effectiveness has been a key area of discussion for long. …"
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Potential Therapeutic Effects of Lebanese Cannabis oil in Female Mouse Models of Neuropsychiatric Disorders
منشور في 2022"…Accordingly, the current research study examined the therapeutic effects of Cannabis oil extracted from the Lebanese Cannabis sativa plant on resilience to stress and its ability to rescue depression and anxiety-like behaviors in female animal models. …"
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masterThesis -
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Stability and bifurcation analysis of a discrete-time predator-prey model with strong Allee effect
منشور في 2020"…In this paper, we investigate the impact of Allee effect on the stability of a discrete-time predator-prey model with a non-monotonic functional response. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma
منشور في 2023"…Intraperitoneal treatment of mice with COE (10, 25 or 50 mg/kg; 9 weeks) showed a non-significant decrease in tumor volume with respect to control, without adverse effects on liver and kidney function. …"
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احصل على النص الكامل
masterThesis -
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How effective are synthetic attack models to detect real-world energy theft?
منشور في 2025"…However, available datasets lack annotated real anomalies, which poses significant challenges in developing effective detection systems. …"