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1
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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2
The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
منشور في 2010"…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …"
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3
Examining time-to-transport decisions in Emergency Medical Services
منشور في 2024"…The Schoenfeld plot (Figure 2) demonstrates that multiple variables have a significant impact on increasing the time-to-handover.…"
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4
Masked phenomenon: renal and cardiovascular complications; review and updates
منشور في 2024"…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). The potential extension of the observed benefits of MP therapy, including a reduction in end-organ damage, remains questionable.…"
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5
A component analysis of positive behaviour support plans
منشور في 2012"…The most commonly implemented components of intervention were setting event changes and quality-of-life-based interventions. …"
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6
Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions
منشور في 2017"…Temperature affects significantly the rheological behavior of neat water Wyoming Na-bentonite dispersions. …"
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7
A clustering metaheuristic for large orienteering problems
منشور في 2022"…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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8
Multilayer Reversible Data Hiding Based on the Difference Expansion Method Using Multilevel Thresholding of Host Images Based on the Slime Mould Algorithm
منشور في 2022"…In the DE-based RDH method, finding spaces that create less distortion in the marked image is a significant challenge, and has a high insertion capacity. …"
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9
Particle size impact on pyrolysis of multi-biomass: a solid-state reaction modeling study
منشور في 2023"…<p dir="ltr">yrolysis has gained significant attention due to its generation of value-added products from waste feeds in an environmentally friendly manner. …"
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10
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (p < 0.05). …"
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11
OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo...
منشور في 2023"…<p dir="ltr">This study reveals a significant connection between prenatal bonding or attachment during pregnancy and various factors such as maternal age, anxiety, and stress, including those attributed to specific events like the COVID-19 pandemic. …"
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12
Oral contraceptive pills and possible adverse effects
منشور في 2014"…Since their introduction to the market, there have been significant changes in the drug content and formulations of these products, in part to decrease the risk of adverse effects. …"
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13
Why do some countries produce more capital intensive output than others?
منشور في 2016"…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …"
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14
Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma
منشور في 2004"…The presence of hepatitis did not significantly affect the survival rate, but hepatic fibrosis and vascular invasion predicted a decreased survival rate. …"
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15
Strengthening of thin reinforced concrete slabs with CFRP laminates
منشور في 2016"…Over the years, engineers and researchers have been working continuously to reduce the dead loads on buildings by reducing the sizes of structural elements. Slabs add significant dead load to buildings compared to other structural members. …"
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16
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …"
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17
DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
منشور في 2019"…<p>Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. …"
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18
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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19
Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis
منشور في 2025"…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …"
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20
Characteristics of aerosols and planetary boundary layer dynamics during biomass burning season
منشور في 2025"…The results illustrate the key contributors to this haze event and showed the there is significant increases in aerosol components such as sulfate, black carbon, organic carbon, dust and aerosol optical depth (AOD). …"