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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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A case exploration of the critical success factors of innovation labs: implications for the UAE
منشور في 2017"…Considering the need to investigate and analyse existing innovation labs within UAE, a case study following qualitative approach was selected for this dissertation. …"
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Obesity in Qatar: A Case-Control Study on the Identification of Associated Risk Factors
منشور في 2020"…Overall, the net effect of hypothesized protective factors of obesity on bone mass seems to have surpassed the hypothesized harmful factors. …"
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Factors affecting university image among undergraduate students: the case study of qatar university
منشور في 2021"…This is especially the case in the Gulf Cooperation Countries, where there has been significant growth in higher education institutions. …"
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Inferior Vena Cava Thrombosis in a Patient with Factor V Leiden Syndrome Presenting with Scrotal Pain
منشور في 2023"…<div><p>Thrombosis in the inferior vena cava (IVC) is a rare but serious condition that can lead to significant morbidity and mortality. We present a case report of a 39-year-old male who presented to the emergency department with right flank pain that had progressed to severe back pain, bilateral flank pain, scrotal pain, and leg pain over the course of two days. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Prevalence, risk factors and outcome of neonatal Pulmonary hemorrhage in extremely preterm infants: A case control study
منشور في 2023"…<h3>Objectives</h3> <p>To determine the prevalence of Pulmonary Hemorrhage (PH) in extremely preterm (EP) babies born before 28 weeks of gestation and evaluate the associated risk factors and outcomes.</p> <h3>Methods</h3> <p>This was a retrospective case-control study involving 45 EP babies born between 2015-2019 who met the criteria for PH. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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Do Pre-Training and Post-Training Factors Impact IT Training Transfer to the workplace? A Case Study from a Multinational Company in the UAE
منشور في 2016"…The results indicate that pre-training and post-training factors significantly influence IT training transfer to the workplace. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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