Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…<p>This systematic review aims to summarise the clinical outcomes of l-glutamine, crizanlizumab, and voxelotor in the treatment of sickle cell disease (SCD) based on clinical trials and real-world data and to identify any gaps in the observations. …"

Board changes and CEO turnover حسب Dah, Mustafa A.

"…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …"

Vocal Changes in Patients With Polycystic Ovary Syndrome حسب Hannoun, Antoine

"…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …"
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Essays on the effect of excess compensation and governance changes on firm value حسب Dah, Mustafa A.

"…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …"
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS حسب Anna Halama (545988)

"…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …"

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership حسب JASIM, ARIF FADHEL AHMED

"…Leaders’ capacity to think about abstract and complex ideas has long been acknowledged as essential to leadership tasks such as planning and analysis; however, because conceptualisation is often ambiguous and difficult to understand, many frameworks of leadership and change lack clarity on the actual significance of leaders’ conceptual skills when leading change. …"
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Swimming exercise improves short‐ and long‐term memories: Time‐course changes حسب Mahmoud A. Alomari (14780446)

"…In this investigation, changes in the spatial hippocampal memory following a time-course of swimming exercise training were examined. …"

Exploring urban growth–climate change–flood risk nexus in fast growing cities حسب Salah Basem Ajjur (14150967)

"…In addition, Doha witnessed various climatic changes with a notable increase in air temperature (+ 8.7%), a decrease in surface wind speed (− 19.5%), and a decrease in potential evapotranspiration losses (− 33.5%). …"

Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition حسب Bouclaous, Carmel

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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study حسب Almu'atasim Khamees (11875640)

"…Most of our sample's smoker participants experienced a change in their smoking level mostly, an increase. …"

Anti-amyloid monoclonal antibody therapies in Alzheimer’s disease – a scoping review حسب Shahd Abubaker Elamin (22569539)

"…This review highlights the need for rigorous, diverse, and patient-centered research. Addressing these gaps is critical in ensuring safe, effective, and equitable treatment for all patients living with Alzheimer’s disease.…"

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">BMI decreased by 3.8 kg/m² 21 days postoperatively. …"

Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing حسب Sulaiman Khan (12585349)

"…Also, it aims to suggest enhanced solutions to address these gaps. In this comprehensive systematic research work, the existing literature reported during 2011 to 2021, is thoroughly analysed for identifying the efforts made to facilitate the doctors and practitioners for diagnosing diseases using healthcare big data analytics. …"

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers حسب Yadav, Santosh K.

"…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …"
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A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats حسب Zeeni, Nadine

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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury حسب Sebnem Garip Ustaoglu (18460611)

"…Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …"

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... حسب Marissa B Reitsma (8674341)

"…</p><p><br></p><h3>Methods</h3><p dir="ltr">We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. …"