Detection of statistically significant network changes in complex biological networks حسب Raghvendra Mall (581171)

"…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …"

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene حسب Zalloua, Pierre

"…The GG genotype was also significantly higher among patients (12.6%) than in controls (4.2%). χ2 analysis and family-based association studies were performed and suggested the association of CTLA4 exon 1 G polymorphism with T1D (p = 0.0229). …"
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Efficient experimental design for uncertainty reduction in gene regulatory networks حسب Roozbeh Dehghannasiri (5725805)

"…Gene regulatory networks often contain a significant amount of uncertainty. …"

Wastewater-based epidemiology for tracking bacterial diversity and antibiotic resistance in COVID-19 isolation hospitals in Qatar حسب A.A., Johar

"…BackgroundHospitals are hotspots for antimicrobial resistance genes (ARGs), and play a significant role in their emergence and spread. …"
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16S rRNA Gene-Based Characterization and Functional Profiling of the Microbiome in Young Adults حسب Makhlouf, Rita

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Correlation of Immunological and Histopathological Features with Gene Expression-Based Classifiers in Colon Cancer Patients حسب Simone van de Weerd (18282199)

"…<div><p>The purpose of this study was to evaluate the association between four distinct histopathological features: (1) tumor infiltrating lymphocytes, (2) mucinous differentiation, (3) tumor-stroma ratio, plus (4) tumor budding and two gene expression-based classifiers—(1) consensus molecular subtypes (CMS) plus (2) colorectal cancer intrinsic subtypes (CRIS). …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"

The combinatory effects of diet and exercise on BDNF gene expression حسب Bassil, Maya

"…The present results enrich our understanding of how exercise and different diets coordinate to induce BDNF gene expression and may be used in identifying novel therapeutic targets for depression…"
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Variational Auto Encoder Approach To Find Deferentially Expressed Genes حسب RAHIMAN, NABIL

"…The proposed method makes use of cluster distribution on every latent space and merged weights in the decoder to assign genes to a cluster. My results discovered new sets of genes that were not shown using state-of-the-art techniques and can properly rank the top genes based on their significance in making clustering.…"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
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Gene-specific machine learning model to predict the pathogenicity of BRCA2 variants حسب Mohannad N. Khandakji (13885434)

"…We trained the model on 80% of the expert reviewed variants by the Evidence-Based Network for the Interpretation of Germline Mutant Alleles (ENIGMA) consortium and tested its performance on the remaining 20%, as well as on an independent set of variants of uncertain significance with experimentally determined functional scores.…"

Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis حسب Shilpa Kuttikrishnan (3520079)

Organic micropollutants in aerobic and anaerobic membrane bioreactors: Changes in microbial communities and gene expression حسب Harb, Moustapha

"…Microbial community dynamics, gene expression levels, and antibiotic resistance genes were analyzed using molecular-based approaches. …"
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The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach حسب Hatem, Zayed

"…This study aimed to identify upregulated genes and significant pathways involved in CLBC. …"
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The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach حسب Hatem Zayed (835448)

"…This study aimed to identify upregulated genes and significant pathways involved in CLBC. …"

Associations between telomere attrition, genetic variants in telomere maintenance genes, and non-small cell lung cancer risk in the Jammu and Kashmir population of North India حسب Gh. Rasool Bhat (6701726)

"…Furthermore, we investigated telomere length variation and its relation to NSCLC risk in the same population using dual-labeled fluorescence-based qPCR.</p><h3>Results</h3><p dir="ltr">Our findings revealed significant associations of TERT rs10069690 and POT1 rs10228682 with NSCLC risk (adjusted p-values = 0.019 and 0.002, respectively), while TERF2 rs251796 and rs2975843 showed no significant associations. …"

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Esraa K. Al-Amleh (16023071)

"…</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"

Accelerating Sepsis Diagnosis Through Culture-Free Genomics: Early Findings And Cost-Effectiveness From A Pilot Study حسب Faisal E. Ibrahim (19962788)

Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer حسب Andrea Remo (447375)

"…Pathway enrichment analysis was used to characterize predicted targets of candidate genes. The expression pattern of the most significant MRs was then evaluated by immunohistochemistry (IHC) in two independent cohorts of IBCs (n = 39) and nIBCs (n = 82) and normal breast tissues (n = 15) spotted on tissue microarrays. …"

Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families حسب Yasser Al-Sarraj (11721425)