Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis حسب Ahmed Fouad Algendy (18102706)

"…<h3>Objective</h3><p dir="ltr">The main aim is to compare the risk of severe hypoglycemia associated with the modified-release (MR) gliclazide against glimepiride in diabetic older adults. …"

Ultrasound Triggered Release of Estrone- Targeted Liposomes حسب Kawak, Pierre

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Investigating the acoustic release of doxorubicin from targeted micelles حسب Husseini, Ghaleb

"…We applied low frequency ultrasound as an external stimulus and measured the amount of release of Dox from these folated micelles. The results showed that the percent drug release increases as the power intensity of ultrasound increases. …"
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Kinetics of ultrasonic release of doxorubicin from pluronic P105 micelles حسب Husseini, Ghaleb

"…Above this threshold, the amount of release was shown to increase as the pulse length increased up to 0.6 s. …"
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Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound حسب Turki, Renad

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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer حسب Ahmed, Amal Elsadig Elamir

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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …"

Ultrasound-responsive Nanocarriers in Cancer Treatment: a review حسب Awad, Nahid S.

"…Using smart nanocarriers, the rate of release of the entrapped therapeutic(s) can be increased, and greater exposure of the tumor cells to the therapeutics can be achieved when the nanocarriers are exposed to certain internally (enzymes, pH and temperature) or externally applied (light, magnetic field, and ultrasound) stimuli that trigger the release of their load in a safe and controlled manner, spatially and temporally. …"
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment حسب Mohammad, Najla

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Lacertus fibrosus release in proximal median nerve entrapment- a systematic review حسب Qutaiba N. M. Shah Mardan (20884597)

"…A significant proportion of the patients had a history of unsuccessful conservative or surgical management (prior carpal tunnel release in 10.5%). …"

Accelerated dissolution testing for controlled release microspheres using the flow-through dissolution apparatus حسب Capomacchia, A.C.

"…The effect of increased temperature was determined to be the statistically significant variable.…"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
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Ultrasonically Triggered Release of Folic Acid-Conjugated Liposomes for Breast Cancer Therapy Within Microfluidic Devices حسب AlHazaimeh, Taima Khair Alla

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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

"…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …"
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Release of colloids in saturated porous media under transient hydro-chemical conditions: A pore-scale study حسب Safna Nishad (16932474)

"…<p dir="ltr">The deposition and consequent release of colloids pose a significant challenge to the environment, groundwater quality and human health. …"

Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study حسب Martins, Ana M.

"…The results showed that the drug release increased with increasing power density, as evidenced by the correlation between α and power density. …"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"

Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines حسب Mansour, Najwa

"…Complex 1 demonstrated only marginal activity in the dark; its cytotoxicity increased significantly upon photoactivation with a high phototoxicity index (PI = [IC50 dark]/[IC50 light]) ranging from 39.2‐fold in A549 to over 100‐fold in MDA‐MB‐231. …"
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Esraa K. Al-Amleh (16023071)

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"