Genome-Based Characterization of Bacterial Pathogens Causing Bloodstream Infection حسب Boujanian, Carni

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"

Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems حسب Local Burden of Disease HIV Collaborators (13279180)

"…</p><h3>Conclusions</h3><p dir="ltr">Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. …"

Willingness to participate in genome testing: a survey of public attitudes from Qatar حسب Hanan F. Abdul Rahim (9330201)

"…The success of a national population-based genome program, like the Qatar Genome Program (QGP), depends on the willingness of citizens to donate samples and take up genomic testing services. …"

Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families حسب Yasser Al-Sarraj (11721425)

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects حسب Ilhame Diboun (3522413)

"…This pioneering study provides a reliable estimate of FH prevalence in Qatar based on a significantly large population-based cohort, whilst uncovering the spectrum of genetic variants associated with FH.…"

Hedonic valuation of land protection methods: implications for cluster development. حسب Kling, Robert

"…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …"
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Whole-genome sequencing based molecular characterization of multi-drug resistant isolates of Enterobacter spp. and Klebsiella aerogenes in Lebanon. (c2019) حسب Merhi, Georgi S.

"…Results were further confirmed through complimentary PCR assays and plasmid-based replicon typing (PBRT). Phylogenetic relatedness was assessed through whole-genome average nucleotide identity (wgANI) and core-genome single nucleotide polymorphism (cgSNP) based phylogenetic analysis. …"
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Whole-genome Sequences of Multidrug-Resistant Escherichia coli حسب Khodor, Ragheed R.

"…Genome comparison, multilocus sequence typing (MLST), and whole-genome SNP-based phylogenetic analysis (wgSNP) were used to determine the relatedness of the isolates. …"
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Hemodynamics of small aneurysm pairs at the internal carotid artery حسب Jou, Liang-Der

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Distinct genomic features across cytolytic subgroups in skin melanoma حسب Constantinos Roufas (4871131)

"…Mutational signatures and kataegis were explored using SigProfiler and compared to the known single or doublet base substitution signatures from COSMIC.</p> <h2>Results</h2> <p>Metastatic skin melanomas had significantly higher CYT levels compared to primary tumors. …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"

Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study حسب Mona Abdi (10196665)

"…Moreover, it uncovers a significant role for recessive variation in ASD architecture in consanguineous settings and provides a unique resource of Middle Eastern genomes for future research to the global ASD community.…"

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed حسب Bartholomew, Aaron

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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma حسب Abou-Ghazal, Mohamed

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Whole-Genome Sequence Analysis of Carbapenem-Resistant Enterobacteriaceae Recovered from Hospitalized Patients in Lebanon حسب El Khoury, Maria

"…It was also the largest genome-based study in the region, revealing the tremendous heterogeneity, plasmid content, and various resistance determinants circulating in the country. …"
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Comprehensive whole genome sequence analyses yields novel genetic and structural insights for Intellectual Disability حسب Farah R. Zahir (18892108)

"…The <i>de novo</i> assembly resulted in unmasking hidden genome instability that was missed by standard re-alignment based algorithms. …"

Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser حسب Salem, Hayder

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Antibiotic Resistance, Virulence Factors and Whole-Genome Characterization of Enterobacter spp. and Klebsiella aerogenes isolated from hospitals in Lebanon حسب Ghafari, Patricia

"…This study presents a comprehensive whole-genome-based characterization of multidrug resistant and hypervirulent ECC members recovered from clinical settings in Lebanon. …"
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Accelerating Sepsis Diagnosis Through Culture-Free Genomics: Early Findings And Cost-Effectiveness From A Pilot Study حسب Faisal E. Ibrahim (19962788)

"…</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">ONT-based 16S rRNA sequencing offers a rapid, sensitive, and cost-effective alternative to traditional blood cultures for diagnosing neonatal sepsis, with the potential to significantly improve clinical outcomes in NICU settings.…"