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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Audit Quality and the Health of the Health Industry
منشور في 2025احصل على النص الكامل
doctoralThesis -
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
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Image-Based Air Quality Estimation Using Convolutional Neural Network Optimized by Genetic Algorithms: A Multi-Dataset Approach
منشور في 2025"…<p dir="ltr">Air pollution poses significant threats to human health and the environment, making effective monitoring increasingly essential. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
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Zero-shot motor health monitoring by blind domain transition
منشور في 2024"…<p>Continuous long-term monitoring of motor health is crucial for the early detection of abnormalities such as bearing faults (up to 51% of motor failures are attributed to bearing faults). …"
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Temporal self-attention for risk prediction from electronic health records using non-stationary kernel approximation
منشور في 2024"…The experimental results demonstrate that non-stationary kernels significantly outperformed baseline methods for NDCG@10 and Hit@10 metrics in both datasets. …"
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Predictive modelling in times of public health emergencies: patients’ non-transport decisions during the COVID-19 pandemic
منشور في 2025"…However, some patients declined transportation to hospital due to their fear of accessing healthcare facilities. This posed a significant risk to their health outcomes. This study aimed to utilise an extensive dataset, which included the period of the COVID-19 pandemic, in a modern Middle Eastern Emergency Medical Service to comprehend and predict the behaviour of non-transport decisions, a major multi-variable factor in pre-hospital emergency medicine. …"
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Knowledge and Anxiety about COVID-19 in the State of Qatar, and the Middle East and North Africa Region—A Cross Sectional Study
منشور في 2021"…It is important that governments, public health agencies, healthcare workers, and civil society organizations keep themselves updated regarding scientific developments and that they relay messages to the community in an honest, transparent, unbiased, and timely manner.…"
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