يعرض 1 - 20 نتائج من 470 نتيجة بحث عن '(( significant implications increases ) OR ( significant ((we decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.12s تنقيح النتائج
  1. 1
  2. 2

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
  3. 3
  4. 4
  5. 5

    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
  6. 6
  7. 7

    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
  8. 8

    Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

    منشور في 2025
    "…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
  9. 9
  10. 10

    A Strategic Perspective to Leadership Implications by Process Paradigm: An Empirical Study حسب Parameswaran, Hima

    منشور في 2021
    "…Increasingly, organizations have realized that to bring about effective change, they need to emphasize leadership strategies. …"
    احصل على النص الكامل
  11. 11
  12. 12
  13. 13

    Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus حسب Hazrat Bilal (7367477)

    منشور في 2021
    "…Long-term temperature data indicates that the annual mean temperature increased significantly by 1.02 °C between 1987 and 2016, while total rainfall exhibited a slight decreasing trend. …"
  14. 14

    Characteristics and health implications of fine particulate matter near urban road site in Islamabad, Pakistan حسب Sabir Hussain (1332675)

    منشور في 2024
    "…<p dir="ltr">The escalating issue of air pollution has become a significant concern in urban regions, including Islamabad, Pakistan, due to the rise in air <u>pollutant emissions</u> driven by economic and industrial expansion. …"
  15. 15

    Clinical relevance of aortic stiffness in end-stage renal disease and diabetes : implication for hypertension management حسب Bahous, Sola Aoun

    منشور في 2018
    "…In treated hypertensive patients, both diabetes and end-stage renal disease (ESRD) are comorbid conditions associated with increased aortic stiffness and high CVR. Thus, the pathophysiological relationship between aortic stiffness, blood pressure (BP) and CVR may have clinical implication in the management of hypertension. …"
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
    article
  16. 16

    Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

    منشور في 2019
    "…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"
  17. 17
  18. 18
  19. 19

    Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment حسب Amal Sabouni (17046236)

    منشور في 2023
    "…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
  20. 20

    Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

    منشور في 2021
    "…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …"
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
    احصل على النص الكامل
    article