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يعرض 1 - 20 نتائج من 645 نتيجة بحث عن '(( significant improvements across ) OR ( significant i decrease ))', وقت الاستعلام: 0.12s تنقيح النتائج
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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    Distinct genomic features across cytolytic subgroups in skin melanoma حسب Constantinos Roufas (4871131)

    منشور في 2022
    "…SBS7a/b, SBS5 and SBS1 were the most prevalent mutational signatures across both cytolytic subgroups, but SBS1 differed significantly between them. …"
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    Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors حسب Noura Aldous (15429873)

    منشور في 2024
    "…Single-cell analysis revealed high RFX6 expression levels in endocrine clusters across various hESC-derived pancreatic differentiation stages. Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …"
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    Analysing Satellite Imagery Classification under Spatial Domain Shift across Geographic Regions حسب Sara A. Al-Emadi (22827935)

    منشور في 2025
    "…<p dir="ltr">Deep learning models are designed based on the i.i.d. assumption; consequently, they experience a significant performance drop due to the distribution shifts when deployed in real environments. …"
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    STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

    منشور في 2023
    "…Interestingly, NFAT1 is significantly downregulated in STIM1-KO cells and overexpression of NFAT1 reversed the enhanced migration of STIM1-KO cells. …"
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    Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting حسب Aryan Bhambu (18767731)

    منشور في 2025
    "…The computational results demonstrate the superiority of the proposed models through a comparative analysis against state-of-the-art approaches across fifteen significant wave height time series, validated by three error metrics and a statistical test.…"
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

    منشور في 2014
    "…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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    On Time-Dependent Rheology of Sutterby Nanofluid Transport across a Rotating Cone with Anisotropic Slip Constraints and Bioconvection حسب Sohaib Abdal (21347810)

    منشور في 2022
    "…<p dir="ltr">The purpose and novelty of our study include the scrutinization of the unsteady flow and heat characteristics of the unsteady Sutterby nano-fluid flow across an elongated cone using slip boundary conditions. …"
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    Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress حسب Jing Ma (24574)

    منشور في 2022
    "…The concentration of malondialdehyde (MDA) and Cd accumulation (roots and shoots) increased significantly (P < 0.05) under the increasing levels of Cd in all genotypes of B. oleracea while antioxidant (enzymatic or non-enzymatic) capacity and nutritional status of the plants was decreased with varying levels of Cd in the sand. …"
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    Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis حسب Hoda Gad (6470522)

    منشور في 2020
    "…Dipeptidyl peptidase-4 inhibitors (DPP-4i) led to a significant reduction in Hb<sub>A1c</sub> (%) (SMD -0.25) and a non-significant decrease in weight (kg) (SMD -1.06) during Ramadan. …"
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