بدائل البحث:
query processing » text processing (توسيع البحث)
rna processing » _ processing (توسيع البحث), signal processing (توسيع البحث), image processing (توسيع البحث)
query processing » text processing (توسيع البحث)
rna processing » _ processing (توسيع البحث), signal processing (توسيع البحث), image processing (توسيع البحث)
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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OutPyR: Bayesian inference for RNA-Seq outlier detection
منشور في 2020"…Existing solutions either require a large number of samples or do not provide proper statistical significance testing.</p><p dir="ltr">We present a Bayesian model (OutPyR) for identifying abnormal RNA-Seq gene expression counts in datasets, particularly those with a small number of samples. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer
منشور في 2023"…<p dir="ltr">Circular RNAs (circRNAs) are regulatory elements that are involved in orchestrating gene expression and protein functions and are implicated in various biological processes including cancer. Notably, breast cancer has a significant mortality rate and is one of the most common malignancies in women. …"
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Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting
منشور في 2022"…</p><h3>Methods</h3><p dir="ltr">We developed a multi-step process to identify immune-related long non-coding RNA signatures with prognostic connotation in multiple TCGA solid cancer datasets.…"
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
منشور في 2024"…These pathways are crucial for cellular function and stress response, and their dysregulation can have significant implications for the disease processes. …"
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
منشور في 2024"…These pathways are crucial for cellular function and stress response, and their dysregulation can have significant implications for the disease processes. …"
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microRNA 21 and long non-coding RNAs interplays underlie cancer pathophysiology: A narrative review
منشور في 2024"…Non-coding RNAs (ncRNAs) are a diverse group of functional RNA molecules that lack the ability to code for proteins. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …"
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Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition
منشور في 2021"…<h3>Background</h3><p dir="ltr">DNA methylation plays a crucial role in multiple cellular processes such as gene regulation, chromatin stability, and genetic imprinting. …"
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The multiomics analyses of cancer stem cells isolated from solid tumors can provide insight for their immunological characterization.
منشور في 2023"…The nCounter platform (Nanostring) was utilized to assess the hybridization with 800 probes for miRNAs and the RNA seq-based transcriptomic profile (Lexogen) was also assessed.…"