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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Artisanal fishing of spiny lobsters with gillnets — A significant anthropic impact on tropical reef ecosystem
منشور في 2015"…This research aims to understand the impact that this artisanal fishing practice is having on the coastal reef systems analysing its associated fauna (bycatch) and the stock of the target species Panulirus echinatus. The study compared an area which was subjected to intense gillnet fishing against one were the practice was absent. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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A national study on nurses’ retention in healthcare facilities in underserved areas in Lebanon
منشور في 2013"…Rural nurses working in PHC centers were more satisfied than their hospital counterparts on all aspects of work and had significantly higher intention to stay (62.5% compared to 31.5% in hospitals, P < 0.001). …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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The role of protected areas in modulating vegetation response to climatic stressors in hyper-arid ecosystems
منشور في 2025"…Results show that vegetation sensitivity to climate drivers increased significantly post-protection. For example, in Al Reem, the effect of evaporation on NDVI shifted from a non-significant, 28.1 (p = 0.136) before 2006 to a significant, 18.5 (p = 0.007) after protection, while the number of precipitation events lost its prior significance (β = 3.4, p = 0.016 → p = 0.981). …"
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Meta Reinforcement Learning for UAV-Assisted Energy Harvesting IoT Devices in Disaster-Affected Areas
منشور في 2024"…<p dir="ltr">Over the past decade, Unmanned Aerial Vehicles (UAVs) have attracted significant attention due to their potential applications in emergency-response applications, including wireless power transfer (WPT) and data collection from Internet of Things (IoT) devices in disaster-affected areas. …"
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Adaptive response for climate change challenges for small and vulnerable coastal area (SVCA) countries: Qatar perspective
منشور في 2023"…Long-term mitigation efforts would not help them reduce their current or immediate vulnerability in the short-term, as long as large countries with comparably huge populations, economies, heavy industrial dependences, and extreme consumption levels do not change their courses significantly. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Comparative analysis of the value for money factors of PPPs between the UAE and the UK
منشور في 2018"…This study also contributed to research in the field of PPPs in the UAE and the UK. The comparative analysis between the two countries highlighted the similarities and differences in the practice and opened areas for future consideration.…"
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Comparing the effectiveness of concept-based curricula and video-based curricula in ESL primary classrooms
منشور في 2022"…Twenty classroom observations were conducted in grade 5 classrooms to examine the effectiveness of concept-based compared to video-based learning for teaching English grammar. …"
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A comparative overview of wet and dry cooling systems for Rankine cycle based CSP plants
منشور في 2013"…Specifically, the performance of parabolic trough, solar tower and Fresnel CSP plants is compared based on the cooling technology A comparative overview of wet and dry cooling systems for Rankine cycle based CSP plants integrated in each plant’s Rankine steam cycle. …"
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Comparative analysis of surgical management approaches for hydatid liver cysts: conventional vs. minimally invasive techniques
منشور في 2023"…<h3>Introduction</h3><p dir="ltr">Hydatid liver disease is a prevalent condition in endemic areas, particularly in the Middle East and North Africa. …"
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Comparative study of LNG, liquid hydrogen, and liquid ammonia post-release evaporation and dispersion during bunkering
منشور في 2024"…Based on the dispersion behaviours, the hazards of LNG and LH2 are comparable, while LNH3 poses significantly higher hazards. …"