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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Machine Learning Approach for Effective Ranking of Researcher Assessment Parameters
منشور في 2023"…An analysis has been conducted to explore the correlation between parameters and awarding societies, examining the associations between different metrics and specific awarding societies.…"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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Adaptive Effects of Seeing Green Environment on Psychophysiological Parameters When Walking or Running
منشور في 2019"…Study 2 showed that running in a green environment was associated with an increased level of perceived exertion at similar speeds (compared to other color conditions), while exposure to red induced a significant decrease in the level of tension. …"
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Topology and parameter estimation in power systems through inverter-based broadband stimulations
منشور في 2015"…This study describes a method for identifying parameters associated with the power system model. In particular, the proposed algorithm in this study addresses the line parameter and topology identification task in the scope of state estimation. …"
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
منشور في 2022"…As the drill pipe rotational speed increased, the pressure drop decreased slightly until a critical rotatory speed was reached, thereafter, the pressure drop increased markedly. …"
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Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students
منشور في 2022"…In the first regression analysis, controlling for age, body mass, height, and body mass index (BMI), the regression coefficient (B = 0.383, 95% confidence interval [CI] [0.088, 0.679], p < 0.05) associated with body fat indicated that with each additional unit of body fat, the YBT AI increased by 0.383 units. In the second regression analysis, controlling for age, body mass, and BMI, the regression coefficients associated with height (B = −1.692, 95% CI [−3.115, −0.269], p < 0.05] and body fat percentage (B = 0.529, 95% CI [0.075, 0.983], p < 0.05) indicated that with each additional unit of height or body fat percentage, the CMJ AI decreased by 1.692 units and increased by 0.529 units. …"
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Bifidobacterium reduction is associated with high blood pressure in children with type 1 diabetes mellitus
منشور في 2021"…We can conclude that the reduction in the abundance of genus Bifidobacterium could play a significant role in elevating the BP in pediatric T1DM subjects. …"
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Association of microRNAs With Embryo Development and Fertilization in Women Undergoing Subfertility Treatments: A Pilot Study
منشور في 2021"…This study was undertaken to determine if circulating miRNAs reflect the changes associated with the parameters of embryo development and fertilization.…"
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Association of periodontal therapy, with inflammatory biomarkers and complications in COVID-19 patients: a case control study
منشور في 2022"…COVID-19 patients with a history of periodontal therapy were associated with significantly lower D-dimer levels than those without recent records of periodontal therapy.…"
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Association of dyslipidemia, diabetes and metabolic syndrome with serum ferritin levels: a middle eastern population-based cross-sectional study
منشور في 2021"…This study used biochemical parameters obtained from 1928 participants from the Qatar Biobank cohort. …"