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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …"
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Non-Linear Time History Analysis of Moment Frame Structure with Performance-Based Approach on Different Concrete Compressive Strengths
منشور في 2023"…Each bay is 5 meters. The nonlinear concrete model was constructed based on the Razvi (1992) confined mode. …"
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …"
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The impact of nozzle diameter and printing speed on geopolymer-based 3D-Printed concrete structures: Numerical modeling and experimental validation
منشور في 2024"…<p dir="ltr">3D Concrete Printing (3DCP) is a promising technology with significant advantages for the construction industry, encompassing reduced labor costs, diminished carbon dioxide emissions, enhanced time efficiency, improved user convenience, and design flexibility. …"
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Effect of Flexural CFRP Sheets and Plates on Shear Resistance of Reinforced Concrete Beams
منشور في 2014احصل على النص الكامل
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …"
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Strengthening of thin reinforced concrete slabs with CFRP laminates
منشور في 2016"…It was also observed that as the concrete strength increases, the gain in flexural capacity of RC slabs from CFRP reinforcement decreases. …"
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Towards Sustainable Low-Embodied-Carbon Concrete Alternatives
منشور في 2024"…This paper evaluates the benefits of using environmentally sustainable low-embodied carbon alternatives to traditional concrete, as the concrete industry is responsible for significant global greenhouse gas emissions due to its environmental impact. …"
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Carbon Nanotube Effect on the Ductility, Flexural Strength, and Permeability of Concrete
منشور في 2019"…<p>Recently, remarkable types of carbon nanofilaments called carbon nanotubes (CNTs) have raised the interest of many concrete and cementitious composite researchers due to their significant mechanical, electrical, thermal, kinetic, and chemical properties. …"
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Numerical Investigation of Flexural Behavior of Reinforced Concrete (RC) T-Beams Strengthened with Pre-Stressed Iron-Based (FeMnSiCrNi) Shape Memory Alloy Bars
منشور في 2023"…The bars are embedded in a concrete layer attached to the beam’s soffit. Based on the numerical results, it was found that increasing the compression strength from 30 to 60 MPa slightly improves the beam’s strength (by 2%), but it significantly increases its ductility by approximately 45%. …"
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Flexural Bond Performance of Anchored CFRP Laminates to Concrete Beams
منشور في 2021احصل على النص الكامل
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Flexural performance of recycled aggregate concrete beams reinforced with basalt fiber-reinforced polymer or steel bars
منشور في 2025"…The parameters investigated included: (1) concrete mixture (0, 25, 50, and 100% use of recycled concrete aggregates (RCA)) and (2) reinforcement material (steel/BFRP). …"